{"title":"口腔湿度测量对诊断斯约格伦综合征的实用性:将其作为诊断标准的可能性","authors":"","doi":"10.1016/j.ajoms.2024.02.007","DOIUrl":null,"url":null,"abstract":"<div><h3>Objectives</h3><p>To investigate the use of an oral moisture meter to aid in the diagnosis of Sjögren’s syndrome (SS) by measuring the moisture values and salivary flow rate (SFR) simultaneously.</p></div><div><h3>Methods</h3><p>The SFR and moisture values of the dorsum of the tongue and buccal mucosa were measured in 40 patients with SS and 29 healthy controls using an oral moisture meter. In addition, a visual analogue scale (VAS) was used to determine the degree of subjective oral symptoms (xerostomia, decreased saliva production, drinking during eating, oral pain, dysphagia, and dysgeusia).</p></div><div><h3>Results</h3><p>The moisture values of the dorsum of the tongue and buccal mucosa were significantly lower in SS patients than in healthy subjects (both <em>p</em> < 0.01). SFR, especially when measured by the spitting test, correlated positively with the moisture values of the dorsum of the tongue (<em>p</em> < 0.0001) and buccal mucosa (<em>p</em> < 0.0003). Furthermore, the sensitivity, specificity, and accuracy of the oral moisture meter measurements of the dorsum of the tongue and buccal mucosa were 92.5%, 68.9%, and 82.6%, and 70.0%, 82.8%, and 73.9%, respectively. The moisture values of the dorsum of the tongue had a moderate negative correlation with the VAS scores of secondary subjective oral symptoms of xerostomia (oral pain, dysphagia, and dysgeusia), whereas a weak negative correlation was observed for subjective oral symptoms directly related to xerostomia (xerostomia and decreased saliva production).</p></div><div><h3>Conclusions</h3><p>The oral moisture meter accurately reflected the results of the SFR tests and chronic subjective oral symptoms, and therefore might be a diagnostic criterion for SS.</p></div>","PeriodicalId":45034,"journal":{"name":"Journal of Oral and Maxillofacial Surgery Medicine and Pathology","volume":null,"pages":null},"PeriodicalIF":0.4000,"publicationDate":"2024-02-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S221255582400019X/pdfft?md5=58510ca1717972fd1085b9ef3482efa4&pid=1-s2.0-S221255582400019X-main.pdf","citationCount":"0","resultStr":"{\"title\":\"The utility of oral moisture measurement for the diagnosis of Sjögren’s syndrome: Its potential application as a diagnostic criterion\",\"authors\":\"\",\"doi\":\"10.1016/j.ajoms.2024.02.007\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<div><h3>Objectives</h3><p>To investigate the use of an oral moisture meter to aid in the diagnosis of Sjögren’s syndrome (SS) by measuring the moisture values and salivary flow rate (SFR) simultaneously.</p></div><div><h3>Methods</h3><p>The SFR and moisture values of the dorsum of the tongue and buccal mucosa were measured in 40 patients with SS and 29 healthy controls using an oral moisture meter. In addition, a visual analogue scale (VAS) was used to determine the degree of subjective oral symptoms (xerostomia, decreased saliva production, drinking during eating, oral pain, dysphagia, and dysgeusia).</p></div><div><h3>Results</h3><p>The moisture values of the dorsum of the tongue and buccal mucosa were significantly lower in SS patients than in healthy subjects (both <em>p</em> < 0.01). SFR, especially when measured by the spitting test, correlated positively with the moisture values of the dorsum of the tongue (<em>p</em> < 0.0001) and buccal mucosa (<em>p</em> < 0.0003). Furthermore, the sensitivity, specificity, and accuracy of the oral moisture meter measurements of the dorsum of the tongue and buccal mucosa were 92.5%, 68.9%, and 82.6%, and 70.0%, 82.8%, and 73.9%, respectively. The moisture values of the dorsum of the tongue had a moderate negative correlation with the VAS scores of secondary subjective oral symptoms of xerostomia (oral pain, dysphagia, and dysgeusia), whereas a weak negative correlation was observed for subjective oral symptoms directly related to xerostomia (xerostomia and decreased saliva production).</p></div><div><h3>Conclusions</h3><p>The oral moisture meter accurately reflected the results of the SFR tests and chronic subjective oral symptoms, and therefore might be a diagnostic criterion for SS.</p></div>\",\"PeriodicalId\":45034,\"journal\":{\"name\":\"Journal of Oral and Maxillofacial Surgery Medicine and Pathology\",\"volume\":null,\"pages\":null},\"PeriodicalIF\":0.4000,\"publicationDate\":\"2024-02-29\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://www.sciencedirect.com/science/article/pii/S221255582400019X/pdfft?md5=58510ca1717972fd1085b9ef3482efa4&pid=1-s2.0-S221255582400019X-main.pdf\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Journal of Oral and Maxillofacial Surgery Medicine and Pathology\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://www.sciencedirect.com/science/article/pii/S221255582400019X\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q4\",\"JCRName\":\"DENTISTRY, ORAL SURGERY & MEDICINE\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Journal of Oral and Maxillofacial Surgery Medicine and Pathology","FirstCategoryId":"1085","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S221255582400019X","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q4","JCRName":"DENTISTRY, ORAL SURGERY & MEDICINE","Score":null,"Total":0}
引用次数: 0
摘要
方法 使用口腔湿度计测量 40 名斯约戈伦综合征(SS)患者和 29 名健康对照者的舌背和口腔粘膜的唾液流速(SFR)和湿度值。结果 SS 患者的舌背和颊粘膜湿度值明显低于健康人(P 均为 0.01)。SFR与舌背水分值(p <0.0001)和口腔粘膜水分值(p <0.0003)呈正相关,尤其是通过吐痰试验测量时。此外,口腔湿度计测量舌背和口腔黏膜的灵敏度、特异性和准确性分别为 92.5%、68.9% 和 82.6%,以及 70.0%、82.8% 和 73.9%。舌背的湿度值与口腔干燥症继发性主观口腔症状(口腔疼痛、吞咽困难和吞咽困难)的 VAS 评分呈中度负相关,而与口腔干燥症直接相关的主观口腔症状(口腔干燥症和唾液分泌减少)则呈弱负相关。
The utility of oral moisture measurement for the diagnosis of Sjögren’s syndrome: Its potential application as a diagnostic criterion
Objectives
To investigate the use of an oral moisture meter to aid in the diagnosis of Sjögren’s syndrome (SS) by measuring the moisture values and salivary flow rate (SFR) simultaneously.
Methods
The SFR and moisture values of the dorsum of the tongue and buccal mucosa were measured in 40 patients with SS and 29 healthy controls using an oral moisture meter. In addition, a visual analogue scale (VAS) was used to determine the degree of subjective oral symptoms (xerostomia, decreased saliva production, drinking during eating, oral pain, dysphagia, and dysgeusia).
Results
The moisture values of the dorsum of the tongue and buccal mucosa were significantly lower in SS patients than in healthy subjects (both p < 0.01). SFR, especially when measured by the spitting test, correlated positively with the moisture values of the dorsum of the tongue (p < 0.0001) and buccal mucosa (p < 0.0003). Furthermore, the sensitivity, specificity, and accuracy of the oral moisture meter measurements of the dorsum of the tongue and buccal mucosa were 92.5%, 68.9%, and 82.6%, and 70.0%, 82.8%, and 73.9%, respectively. The moisture values of the dorsum of the tongue had a moderate negative correlation with the VAS scores of secondary subjective oral symptoms of xerostomia (oral pain, dysphagia, and dysgeusia), whereas a weak negative correlation was observed for subjective oral symptoms directly related to xerostomia (xerostomia and decreased saliva production).
Conclusions
The oral moisture meter accurately reflected the results of the SFR tests and chronic subjective oral symptoms, and therefore might be a diagnostic criterion for SS.