确定肿瘤细胞性肾肿瘤的诊断：一份病例报告

Diagnostic Histopathology Pub Date : 2024-02-27 DOI:10.1016/j.mpdhp.2024.02.005

Clare McGenity, Simon Vlies, Jo-An Roulson

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引用次数: 0

摘要

这是一名 45 岁男性患者的病例，他患有难以分类的肿瘤性肾肿瘤。肾部分切除术的组织学检查显示，肿瘤由肿瘤细胞组成，细胞核呈圆形，有一些突出的核仁，但没有坏死或淋巴管侵犯。CK7 免疫组化呈灶性阳性，CD117 仅呈弱染色。肿瘤细胞性肾肿瘤的鉴别诊断需要考虑多种病变，其特征介于肿瘤细胞瘤和嗜铬细胞癌之间。分子病理学的应用日益广泛，这对某些实体的诊断也很重要。

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Determining the diagnosis of an oncocytic renal neoplasm: a case report

This is the case of a 45 year old male patient with an oncocytic renal neoplasm that was difficult to classify. Histology from a partial nephrectomy revealed a tumour comprising oncocytic cells containing rounded nuclei with some prominent nucleoli, although no necrosis or lymphovascular invasion. CK7 immunohistochemistry was focally positive, with only weak staining for CD117. There are multiple lesions to consider in the differential diagnosis of oncocytic renal tumours with borderline features between oncocytoma and chromophobe carcinoma. The increasing use of molecular pathology is also important in the diagnosis of some entities.

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来源期刊

Diagnostic Histopathology Medicine-Pathology and Forensic Medicine

CiteScore

1.30

自引率

0.00%

发文量

期刊介绍： This monthly review journal aims to provide the practising diagnostic pathologist and trainee pathologist with up-to-date reviews on histopathology and cytology and related technical advances. Each issue contains invited articles on a variety of topics from experts in the field and includes a mini-symposium exploring one subject in greater depth. Articles consist of system-based, disease-based reviews and advances in technology. They update the readers on day-to-day diagnostic work and keep them informed of important new developments. An additional feature is the short section devoted to hypotheses; these have been refereed. There is also a correspondence section.