T. D. Le, Da Vy Thi Le, T. H. Tran, P. Dang, T. Le, Mai Thanh Thi Nguyen, N. Nguyen
{"title":"Taxus wallichiana（紫杉科）叶片的化学成分","authors":"T. D. Le, Da Vy Thi Le, T. H. Tran, P. Dang, T. Le, Mai Thanh Thi Nguyen, N. Nguyen","doi":"10.1002/vjch.202300059","DOIUrl":null,"url":null,"abstract":"From CHCl3‐soluble extract of the leaves of Taxus wallichiana (Taxaceae), collected in Lam Dong Province, five compounds were isolated and identified as sciadopitysin (1), ginkgetin (2), (S)‐(+)‐rhododenol (3), (+)‐erythro‐N‐benzoyl‐3‐phenylisoserine methyl ester (4), and (−)‐α‐conidendrin (5). Their chemical structures were determined by 1D and 2D NMR spectra and comparison with published data. Except for (−)‐α‐conidendrin, these remaining compounds were first reported of Taxus wallichiana. Among these compounds, ginkgetin (2), and (−)‐α‐conidendrin (5) showed significant α‐glucosidase inhibitory activity with the IC50 values of 98.5, and 172.1 µm, respectively.","PeriodicalId":23525,"journal":{"name":"Vietnam Journal of Chemistry","volume":null,"pages":null},"PeriodicalIF":1.3000,"publicationDate":"2024-02-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Chemical constituents of the leaves of Taxus wallichiana (Taxaceae)\",\"authors\":\"T. D. Le, Da Vy Thi Le, T. H. Tran, P. Dang, T. Le, Mai Thanh Thi Nguyen, N. Nguyen\",\"doi\":\"10.1002/vjch.202300059\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"From CHCl3‐soluble extract of the leaves of Taxus wallichiana (Taxaceae), collected in Lam Dong Province, five compounds were isolated and identified as sciadopitysin (1), ginkgetin (2), (S)‐(+)‐rhododenol (3), (+)‐erythro‐N‐benzoyl‐3‐phenylisoserine methyl ester (4), and (−)‐α‐conidendrin (5). Their chemical structures were determined by 1D and 2D NMR spectra and comparison with published data. Except for (−)‐α‐conidendrin, these remaining compounds were first reported of Taxus wallichiana. Among these compounds, ginkgetin (2), and (−)‐α‐conidendrin (5) showed significant α‐glucosidase inhibitory activity with the IC50 values of 98.5, and 172.1 µm, respectively.\",\"PeriodicalId\":23525,\"journal\":{\"name\":\"Vietnam Journal of Chemistry\",\"volume\":null,\"pages\":null},\"PeriodicalIF\":1.3000,\"publicationDate\":\"2024-02-13\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Vietnam Journal of Chemistry\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.1002/vjch.202300059\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q3\",\"JCRName\":\"CHEMISTRY, MULTIDISCIPLINARY\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Vietnam Journal of Chemistry","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1002/vjch.202300059","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q3","JCRName":"CHEMISTRY, MULTIDISCIPLINARY","Score":null,"Total":0}
Chemical constituents of the leaves of Taxus wallichiana (Taxaceae)
From CHCl3‐soluble extract of the leaves of Taxus wallichiana (Taxaceae), collected in Lam Dong Province, five compounds were isolated and identified as sciadopitysin (1), ginkgetin (2), (S)‐(+)‐rhododenol (3), (+)‐erythro‐N‐benzoyl‐3‐phenylisoserine methyl ester (4), and (−)‐α‐conidendrin (5). Their chemical structures were determined by 1D and 2D NMR spectra and comparison with published data. Except for (−)‐α‐conidendrin, these remaining compounds were first reported of Taxus wallichiana. Among these compounds, ginkgetin (2), and (−)‐α‐conidendrin (5) showed significant α‐glucosidase inhibitory activity with the IC50 values of 98.5, and 172.1 µm, respectively.
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