绝经后的幼年颗粒细胞瘤

Inés Cortiñas Díez, María Fernanda Berzal Cantalejo, María López-Menéndez Arqueros
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引用次数: 0

摘要

颗粒细胞瘤是一种罕见的卵巢肿瘤。组织学上分为两种类型:成人型和幼年型。幼年颗粒细胞瘤占 5%,其中只有 3% 发生在 30 岁以上的人群中。鉴于其罕见性和容易与其他卵巢肿瘤混淆的特点,术中明确诊断非常复杂。囊性形态的未成熟颗粒细胞、频繁的有丝分裂、无 Call-Exner 体和免疫囊性研究证实了这一点。该病发病率低,因此很难诊断。疾病的分期是最重要的预后因素,完全切除是必不可少的。辅助治疗的作用尚未得到很好的确定,现有的研究只包括极少数病例,而且没有对成年女性进行区分。为早期发现可能的晚期复发而进行充分的随访是一项临床挑战。关键词:颗粒细胞瘤颗粒细胞瘤 幼年颗粒细胞瘤 卵巢肿瘤 更年期
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Tumor de células de la granulosa tipo juvenil tras la menopausia
Granulosa cell tumors are rare ovarian tumors. There are two histological types: adult and juvenile. Juvenile granulosa cell tumors account for 5%, with only 3% occurring in people over 30 years of age. Given the suspicion, the definitive intraoperative diagnosis is complex given its rarity and its easy confusion with other ovarian neoplasms. The cystic pattern with immature granulosa cells, with frequent mitosis, the absence of Call-Exner bodies and the immunocystic study confirm this. Its low prevalence makes it difficult to diagnose. The stage of the disease is the most important prognostic factor, and complete resection is essential. The role of complementary therapy is not well established, and the available studies include only a minimal number of cases, which do not differentiate between adult women. Adequate follow-up for the early detection of a possible late recurrence is a clinical challenge. Keywords: Granulosa cell tumor, Juvenile granulosa cell tumor, Ovarian neoplasms, Menopause.
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