Inés Cortiñas Díez, María Fernanda Berzal Cantalejo, María López-Menéndez Arqueros
{"title":"绝经后的幼年颗粒细胞瘤","authors":"Inés Cortiñas Díez, María Fernanda Berzal Cantalejo, María López-Menéndez Arqueros","doi":"10.51288/00840113","DOIUrl":null,"url":null,"abstract":"Granulosa cell tumors are rare ovarian tumors. There are two histological types: adult and juvenile. Juvenile granulosa cell tumors account for 5%, with only 3% occurring in people over 30 years of age. Given the suspicion, the definitive intraoperative diagnosis is complex given its rarity and its easy confusion with other ovarian neoplasms. The cystic pattern with immature granulosa cells, with frequent mitosis, the absence of Call-Exner bodies and the immunocystic study confirm this. Its low prevalence makes it difficult to diagnose. The stage of the disease is the most important prognostic factor, and complete resection is essential. The role of complementary therapy is not well established, and the available studies include only a minimal number of cases, which do not differentiate between adult women. Adequate follow-up for the early detection of a possible late recurrence is a clinical challenge. Keywords: Granulosa cell tumor, Juvenile granulosa cell tumor, Ovarian neoplasms, Menopause.","PeriodicalId":515382,"journal":{"name":"Revista de Obstetricia y Ginecología de Venezuela","volume":"13 s1","pages":""},"PeriodicalIF":0.0000,"publicationDate":"2024-02-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Tumor de células de la granulosa tipo juvenil tras la menopausia\",\"authors\":\"Inés Cortiñas Díez, María Fernanda Berzal Cantalejo, María López-Menéndez Arqueros\",\"doi\":\"10.51288/00840113\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"Granulosa cell tumors are rare ovarian tumors. There are two histological types: adult and juvenile. Juvenile granulosa cell tumors account for 5%, with only 3% occurring in people over 30 years of age. Given the suspicion, the definitive intraoperative diagnosis is complex given its rarity and its easy confusion with other ovarian neoplasms. The cystic pattern with immature granulosa cells, with frequent mitosis, the absence of Call-Exner bodies and the immunocystic study confirm this. Its low prevalence makes it difficult to diagnose. The stage of the disease is the most important prognostic factor, and complete resection is essential. The role of complementary therapy is not well established, and the available studies include only a minimal number of cases, which do not differentiate between adult women. Adequate follow-up for the early detection of a possible late recurrence is a clinical challenge. Keywords: Granulosa cell tumor, Juvenile granulosa cell tumor, Ovarian neoplasms, Menopause.\",\"PeriodicalId\":515382,\"journal\":{\"name\":\"Revista de Obstetricia y Ginecología de Venezuela\",\"volume\":\"13 s1\",\"pages\":\"\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2024-02-22\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Revista de Obstetricia y Ginecología de Venezuela\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.51288/00840113\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Revista de Obstetricia y Ginecología de Venezuela","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.51288/00840113","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
Tumor de células de la granulosa tipo juvenil tras la menopausia
Granulosa cell tumors are rare ovarian tumors. There are two histological types: adult and juvenile. Juvenile granulosa cell tumors account for 5%, with only 3% occurring in people over 30 years of age. Given the suspicion, the definitive intraoperative diagnosis is complex given its rarity and its easy confusion with other ovarian neoplasms. The cystic pattern with immature granulosa cells, with frequent mitosis, the absence of Call-Exner bodies and the immunocystic study confirm this. Its low prevalence makes it difficult to diagnose. The stage of the disease is the most important prognostic factor, and complete resection is essential. The role of complementary therapy is not well established, and the available studies include only a minimal number of cases, which do not differentiate between adult women. Adequate follow-up for the early detection of a possible late recurrence is a clinical challenge. Keywords: Granulosa cell tumor, Juvenile granulosa cell tumor, Ovarian neoplasms, Menopause.