同化雄性类固醇:综述

Siya Rohilla, Prerna Sharma, Sweta Kamboj, Sanchit Dhankar, Nitika Garg, Samrat Chauhan, Nidhi Rani
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摘要

很多运动员、健美运动员和那些想让自己看起来更漂亮的人都会使用 AAS(合成代谢雄性类固醇)来实现自己的目标。类固醇可以在自然界中找到,也可以在实验室中合成。这些物质试图模仿睾酮的合成代谢(增肌)和雄激素(男性化)特性。睾酮、甲地孕酮、癸酸诺龙(ND)和美替诺龙等类固醇只是常见滥用的 AAS 的几个例子。这些物质最初是专业健美运动员的专用物质,现在越来越多的业余和专业运动员都在尝试使用。合成代谢类兴奋剂的同化特性使其被用于治疗慢性肾病和绝经后妇女骨质疏松症等疾病。尽管世界反兴奋剂机构明令禁止使用合成类固醇,但据估计,美国普通人群中合成类固醇的使用率在 1%到 3%之间(世界反兴奋剂机构)。类固醇对包括心血管和生殖系统在内的多个器官的负面影响已引起人们的关注。因此,不适当地使用合成类兴奋剂会对健康造成严重危害。需要对公众和医疗专业人员进行更多的教育,让他们了解如何识别症状、进行有效护理和预防与合成类兴奋剂相关的疾病。本研究的目的是考察我们目前对AAS的功能及其相关有害后果的认识状况。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Anabolic Androgenic Steroids: A Review
A lot of athletes, bodybuilders, and those who want to look better in general use AAS (anabolic androgenic steroids) to achieve their goals. These steroids can be found in nature or synthesised in a lab. These substances are attempts to mimic the anabolic (muscle-building) and androgenic (masculinizing) properties of testosterone. Steroids like testosterone, methandienone, Nandrolone Decanoate (ND), and methenolone are only a few examples of AAS that are commonly abused. Initially exclusive to professional bodybuilders, these substances are increasingly being tried out by amateur and professional athletes alike. The anabolic properties of AAS have led to their usage in medicine for the treatment of conditions like chronic renal disease and osteoporosis in postmenopausal women. Despite being banned by the World Anti-Doping Agency, anabolic steroid (AAS) use is estimated to be between 1% and 3% among the general population of the United States (WADA). Their negative effects on several organs, including the cardiovascular and reproductive systems, have aroused concerns. Therefore, there are serious health risks linked with the inappropriate use of AAS. More education is needed for both the general public and medical professionals on how to recognise symptoms, administer effective care, and prevent AAS-related disorders. The goal of this study is to examine the current state of our understanding regarding the functioning of AAS and their associated deleterious consequences.
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