Association of Socio-demographic factors with Polycystic Ovarian Syndrome; A Comparative Study

Objective: To compare the association of Socio-demographic factors in Polycystic Ovarian Syndrome (PCOS) patients with healthy controls. Study Design: Comparative cross-sectional study. Place and Duration of Study: Department of Biochemistry and Molecular Biology, Army Medical College, Rawalpindi, Pakistan, in collaboration with Department of Gynecology and Obstetrics PEMH, Rawalpindi, Pakistan from Apr to Aug 2023. Methodology: The study comprised 300 females within reproductive age groups. Participants were separated into two groups. Group-I included 150 diagnosed PCOS patients, and Group-II had 150 healthy females selected by non-probability purposive sampling. Results: The PCOS patients exhibit a higher mean weight than the control Group (p-value; 0.017). The comparison of PCOS patients and controls showed significant association with physical activity (p-value: 0.038), hirsutism (p-value: 0.010) and Ferriman-Gallwey score (p-value: 0.001) and consanguineous marriages (p-value:  0.076). Conclusion: This study underscores the significance of socio-demographic factors in the manifestation of PCOS in Pakistan, emphasizing the need for early diagnosis, intervention, and tailored healthcare strategies, particularly among young women.