甲状腺功能正常的 2 型糖尿病患者血红蛋白和血清胆红素水平与血糖控制的关系 - 一项回顾性研究

Jayanthi Rajendran, Priyanka A.
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引用次数: 0

摘要

背景:糖尿病及其并发症会降低铁的吸收,从而增加贫血的风险。在糖尿病患者中,甲状腺疾病的发病率为 14.7%。在 13% 的 T2DM 患者中,亚临床甲状腺功能减退症是最常见的甲状腺疾病。甲状腺功能障碍可能会影响糖尿病的糖代谢,血液中促甲状激素的变化与糖化血红蛋白的变化有关。研究方法对在全科医学科门诊就诊的甲状腺功能正常的 2 型糖尿病患者进行回顾性研究分析。通过适当程序获取医院病历(MRD 病史)作为信息来源。研究组收集了四年内患有 2 型糖尿病(FBS>126)且无任何明显甲状腺疾病临床表现的患者的数据。研究结果PBS、HbA1C、低密度脂蛋白、促甲状腺激素与空腹血糖的关系非常显著(P=0.00)。FBS 和 RBC 与 HbA1C 的关系非常显著(P=0.00)。尿酸、胆固醇、直接胆红素、血红蛋白与胆红素呈高度显著性(P=0.00),而胆固醇、总胆红素与血红蛋白呈高度显著性(P=0.00)。血红蛋白与 FT4 呈正相关。胆固醇与血红蛋白(HbA1c≥7)呈强负相关。促甲状腺激素与 FBS 相关。直接胆红素与 FBS 和总胆固醇(HbA1c ≥‰¤7)呈正相关。结论我们的研究结果表明,甲状腺状态、血红蛋白和全血细胞计数可作为T2DM患者的有用工具。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
ASSOCIATION OF EUTHYROID TYPE 2 DIABETES MELLITUS WITH HEMOGLOBIN AND SERUM BILIRUBIN LEVELS RELATING TO GLYCEMIC CONTROL - A RETROSPECTIVE STUDY
Background: Diabetes, along with its comorbidities, may increase the risk of anaemia by lowering iron absorption. In diabetic patients, thyroid illness was 14.7% prevalent. In 13% of T2DM patients, subclinical hypothyroidism was the most common thyroid condition. Diabetes glucose metabolism may be impacted by thyroid dysfunction, and variations in blood TSH have been linked to variations in glycatedhaemoglobin. Methodology: Retrospective study analysis of euthyroid type 2 diabetic patients who had attended the OPD in the department of General Medicine. The hospital records (case history from MRD) were used as the sources of information by following proper procedure in obtaining the same. Collection of data for a period of four years with Type 2 diabetes (FBS>126) and who did not possess any obvious clinical manifestations of thyroid disease was included for the study group. Results: PBS, HbA1C, LDL, TSH are highly significant with Fasting blood sugar with(p=0.00). FBS, RBC are highly significant with HbA1C (p=0.00). Uric acid, cholesterol,directbilirubin,haemoglobinishighlysignificantwithbilirubin(p=0.00).whereascholesterol, total billirubin are highly significant with haemoglobin (p=0.00). Hb showedpositive association with FT4. TAG, VLDL, Globulin showed negative association with FBS.HbisnegativelyassociatedwithTotalbilirubin.Cholesterolexhibitsstrongnegativeassociation with Hemoglobin (HbA1c ≥7). TSHwere associated with FBS. Direct bilirubinexhibits positive association with FBS and TotalCholesterol(HbA1c ≤7). Conclusion: Our study results outcome could be concluded that the thyroid status, haemoglobinandCBCcouldbeusefultoolforT2DMpatients.
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