普拉德-威利综合征患者的高血压 :病例报告和文献综述

G. Ziani, N. Belharty, M. Cherti
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引用次数: 0

摘要

普拉德-威利综合征(PWS)是导致肥胖的最常见遗传病因,其特点是所有年龄段的死亡率都很高。在这种情况下,非肥胖的普氏综合征患者出现代谢综合征(MetS)的频率较低,而在肥胖的普氏综合征患者和肥胖对照组中则观察到高血压的高发率。本报告的目的是估算一大群患有帕金森氏症的成年人中高血压的发生率及其组成部分。研究发现,该综合征与心血管疾病死亡率升高有关,但其潜在机制尚不完全清楚。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
HIGH BLOOD PRESSURE IN PATIENTS WITH PRADER WILLI SYNDROME : CASE REPORT AND REVIEW OF THE LITERATURE
Prader-Willi syndrome (PWS), the most common genetic cause of obesity, is characterized by elevated morbi-mortality in all ages. In this context, non-obese PWS patients showed low frequency of metabolic syndrome (MetS), while a high prevalence of hypertension was observed in obese PWS and obese controls. The aim of this report was to estimate the occurrence of high blood pressure and its components in a large group of PWS adults. An association of this syndrome with elevated cardiovascular morbi-mortality was observed, but the underlying mechanisms are not fully known.
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