自动滴定氧气对心脏手术后重症监护室成人在规定血氧饱和度范围内停留时间的影响

IF 1.4 4区 医学 Q3 CRITICAL CARE MEDICINE
Louis W. Kirton MBChB , Raulle Sol Cruz BSN , Leanlove Navarra BSN , Allie Eathorne BSc , Julie Cook MBChB , Richard Beasley DSc , Paul J. Young MBChB, PhD
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引用次数: 0

摘要

目的本研究旨在确定,对于在重症监护病房(ICU)接受治疗的心脏外科术后患者,与手动调整高流量氧疗相比,自动滴定吸入氧分压(FiO2)是否能延长血氧饱和度(SpO2)在预定目标 SpO2 范围内的时间。干预措施自动调节 FiO2(使用自动氧气控制系统)与手动 FiO2 滴定进行比较,直至停止氧疗、ICU 出院或 24 小时(以时间在前者为准)。结果在 65 名参与者中,自动滴定组(n = 28)和手动滴定组(n = 28)每位患者在 SpO2 目标范围内所用时间的百分比中位数分别为 97.7 %(四分位间范围:87.9-99.2 %)和 91.3 %(四分位间范围:77.1-96.1 %)。与手动 FiO2 滴定相比,自动 FiO2 滴定的估计效果是将目标范围内所用时间的百分比中位数提高了 4.8 个百分点(95 % 置信区间:1.6 至 10.3 个百分点,p = 0.01)。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Effect of automated titration of oxygen on time spent in a prescribed oxygen saturation range in adults in the ICU after cardiac surgery

Objective

The objective of this study was to determine whether automated titration of the fraction of inspired oxygen (FiO2) increases the time spent with oxygen saturation (SpO2) within a predetermined target SpO2 range compared with manually adjusted high-flow oxygen therapy in postoperative cardiac surgical patients managed in the intensive care unit (ICU).

Design

Single-centre, open-label, randomised clinical trial.

Setting

Tertiary centre ICU.

Participants

Recently extubated adults following elective cardiac surgery who required supplemental oxygen.

Interventions

Automatically adjusted FiO2 (using an automated oxygen control system) compared with manual FiO2 titration, until cessation of oxygen therapy, ICU discharge, or 24 h (whichever was sooner).

Main outcome measures

The primary outcome was the proportion of time receiving oxygen therapy with the SpO2 in a SpO2 target range of 92–96 %.

Results

Among 65 participants, the percentage of time per patient spent in the target SpO2 range was a median of 97.7 % (interquartile range: 87.9–99.2 %) and 91.3 % (interquartile range: 77.1–96.1 %) in the automated (n = 28) and manual (n = 28) titration groups, respectively. The estimated effect of automated FiO2, compared to manual FiO2 titration, was to increase the percentage of time spent in the target range by a median of 4.8 percentage points (95 % confidence interval: 1.6 to 10.3 percentage points, p = 0.01).

Conclusion

In patients recently extubated after cardiac surgery, automated FiO2 titration significantly increased time spent in a target SpO2 range of 92–96 % compared to manual FiO2 titration.

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来源期刊
Critical Care and Resuscitation
Critical Care and Resuscitation CRITICAL CARE MEDICINE-
CiteScore
7.70
自引率
3.40%
发文量
44
审稿时长
>12 weeks
期刊介绍: ritical Care and Resuscitation (CC&R) is the official scientific journal of the College of Intensive Care Medicine (CICM). The Journal is a quarterly publication (ISSN 1441-2772) with original articles of scientific and clinical interest in the specialities of Critical Care, Intensive Care, Anaesthesia, Emergency Medicine and related disciplines. The Journal is received by all Fellows and trainees, along with an increasing number of subscribers from around the world. The CC&R Journal currently has an impact factor of 3.3, placing it in 8th position in world critical care journals and in first position in the world outside the USA and Europe.
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