按症状亚型对与慢性失眠的存在和加重相关的因素进行横断面分析

Masumi Osao, I. Okajima, Yuichi Inoue
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摘要

本研究旨在通过症状亚型及其对日间功能障碍的影响,调查心理和时间生物学因素与慢性失眠的存在和严重程度之间的关联。本网络流行病学研究的参与者被分为以下几类:入睡困难(DIS)(n = 91);维持睡眠困难(DMS)(n = 13);早醒(EMA)(n = 48);DIS + DMS(n = 67);DIS + EMA(n = 23);DMS + EMA(n = 24);DIS、DMS 和 EMA 三重症状(TRP)(n = 69);正常睡眠者(n = 4590)。对失眠严重程度指数(ISI)、医院焦虑和抑郁量表(HADS)、慕尼黑时间型问卷(MCTQ)、失眠相关心理测量(包括福特失眠应激反应测试(FIRST)和睡眠障碍信念和态度量表(DBAS))以及睡前唤醒量表(PSAS)的认知和躯体领域进行了评估。DIS 和 DIS + DMS 与晚间偏好显著相关,EMA 和 EMA + DMS 与早晨偏好显著相关,而 TRP 与两种时间型均无显著相关。在所有亚型中,DBAS 分数的增加都与 ISI 分数的增加有关。同时,每种心理测量指标的关联在不同失眠亚型中也有所不同,PSAS认知唤醒与DIS相关,PSAS躯体唤醒与DMS + EMA和TRP相关。病理 HADS 评分与所有亚型都有关联。时间类型可能与某些失眠亚型的存在有关;然而,只有心理因素被推测会导致所有亚型的加重。所有失眠亚型都可能导致抑郁症的形成。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Cross‐sectional analyses of factors associated with the presence and aggravation of chronic insomnia by symptom subtypes
The aim of this study was to investigate the association of psychological and chronobiological factors with the presence and severity of chronic insomnia by symptom subtypes and their impacts on daytime dysfunctions.Participants of the present web‐based epidemiological study were classified as follows: difficulty initiating sleep (DIS) (n = 91); difficulty maintaining sleep (DMS) (n = 13); early morning awakening (EMA) (n = 48); DIS + DMS (n = 67); DIS + EMA (n = 23); DMS + EMA (n = 24); triplet of DIS, DMS, and EMA symptoms (TRP) (n = 69); and normal sleepers (n = 4590). The Insomnia Severity Index (ISI), Hospital Anxiety and Depression Scale (HADS), Munich Chronotype Questionnaire (MCTQ), insomnia‐related psychological measures (including the Ford Insomnia Response to Stress Test [FIRST] and the Dysfunctional Beliefs and Attitudes about Sleep Scale [DBAS]), and the cognitive and somatic domains of the Pre‐Sleep Arousal Scale (PSAS) were evaluated.The presence of DIS and DIS + DMS were significantly associated with an evening preference, and EMA and EMA + DMS with a morning preference, while TRP showed no significant association with either chronotype. The increase in DBAS scores was associated with higher ISI scores in all subtypes. Meanwhile, the associations of each psychological measure varied among insomnia subtypes, with the association of PSAS cognitive arousal to DIS and PSAS somatic arousal to both DMS + EMA and TRP. Pathological HADS score was associated with all subtypes.Chronotypes may be associated with the presence of some insomnia subtypes; however, only psychological factors were speculated to contribute to the aggravation of all subtypes. All insomnia subtypes possibly contribute to the formation of depression.
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