β-羟基-β-甲基丁酸对老年人肌肉力量和功能结果的影响

IF 0.4 4区医学 Q4 NUTRITION & DIETETICS

Topics in Clinical Nutrition Pub Date : 2024-03-25 DOI:10.1097/tin.0000000000000362

Joana Mendes, Rita S. Guerra, Ana S Sousa

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引用次数: 0

摘要

人们越来越认识到，营养干预在功能状态中发挥着重要作用。β-羟基-β-甲基丁酸（HMB）是一种必需氨基酸的代谢产物，补充这种物质可能是改善老年人肌肉力量和功能的有效营养干预措施。本综述旨在概述补充 HMB 对老年人的影响，特别是对肌肉力量和功能结果的影响。我们在 PubMed 数据库中进行了搜索，仅纳入了随机对照试验研究。在 14 项分析研究中，有一半以上的研究报告称补充 HMB 可改善肌肉力量和其他功能结果。在不同健康状况和体力活动条件下，补充 HMB 对老年人的肌肉力量和功能结果都有良好的影响。

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The Effect of β-Hydroxy-β-Methylbutyrate on Muscle Strength and Functional Outcomes in Older Adults

Nutritional intervention is increasingly being recognized as playing an important role in functional status. The supplementation with β‑hydroxy-β-methylbutyrate (HMB), which is a metabolite of an essential amino acid, may be an effective nutritional intervention to improve muscle strength and functionality in older adults. The aim of this narrative review was to present an updated overview of the effects of HMB supplementation in older adults, specifically on muscle strength and functional outcomes. A PubMed database search was performed and only randomized controlled trial studies were included. More than half of the 14 analyzed studies reported that HMB supplementation improved muscle strength and other functional outcomes. HMB supplementation has demonstrated some promising effects on muscle strength and functional outcomes in older adults with different conditions of health and physical activity.

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来源期刊

Topics in Clinical Nutrition NUTRITION & DIETETICS-

CiteScore

0.90

自引率

20.00%

发文量

期刊介绍： Topics in Clinical Nutrition (TICN) is a peer-reviewed, quarterly journal designed as a resource for the continuing education and clinical practice of dietitians and nutritionists. Each issue addresses topics of interest primarily to dietitians and nutritionists, students and interns in professional training programs and other health care personnel involved in the nutritional care of patients. Articles include translational research reports (work that applies new knowledge to practical effect), practice projects, evidence-based literature reviews, case studies and book reviews, and articles that highlight education theory and applied research which share the tools and techniques of nutrition and dietetics education.