干细胞介导的热蛋白沉积调节有助于非感染性炎症相关疾病的组织修复（综述）。

IF 8.3 2区材料科学 Q1 MATERIALS SCIENCE, MULTIDISCIPLINARY

ACS Applied Materials & Interfaces Pub Date : 2024-03-29 DOI:10.3892/ijmm.2024.5370

Yi Wei, Li Li, Yiping Wang, Yan Chen, Zhengyang Li, Chufei Huang, Yangchen Wei, Chiyu Jia, Zuo Wang, Junlin Liao

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引用次数: 0

摘要

裂解病是一种具有溶解和炎症特征的程序性细胞死亡，在非感染性炎症相关疾病中起着至关重要的作用，但如果调节失调，则可能导致有害结果。干细胞已成为通过旁分泌信号调节热噬的关键角色，为组织修复和再生提供了一条新途径。本综述深入探讨了以往阐明干细胞与热蛋白沉积之间错综复杂相互作用的研究，强调了基于干细胞的疗法在调节热蛋白沉积途径方面的潜力。对这一动态相互作用的探索，为制定在炎症相关疾病中利用干细胞进行有效组织修复和再生的策略带来了希望。

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Stem cell‑mediated modulation of pyroptosis contributes to tissue repair in noninfective inflammatory‑related diseases (Review).

Pyroptosis, a programmed cell death marked by lytic and inflammatory characteristics, plays a crucial role in non‑infectious inflammation‑related diseases but can lead to detrimental outcomes when dysregulated. Stem cells have emerged as key players in modulating pyroptosis through paracrine signaling, offering a novel avenue for tissue repair and regeneration. The present review delved into previous studies elucidating the intricate interplay between stem cells and pyroptosis, emphasizing the potential of stem cell‑based therapies in regulating pyroptotic pathways. The exploration of this dynamic interaction holds promise for developing strategies to harness stem cells for effective tissue repair and regeneration in the context of inflammation‑related diseases.

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来源期刊

ACS Applied Materials & Interfaces 工程技术-材料科学：综合

CiteScore

16.00

自引率

6.30%

发文量

4978

审稿时长

1.8 months

期刊介绍： ACS Applied Materials & Interfaces is a leading interdisciplinary journal that brings together chemists, engineers, physicists, and biologists to explore the development and utilization of newly-discovered materials and interfacial processes for specific applications. Our journal has experienced remarkable growth since its establishment in 2009, both in terms of the number of articles published and the impact of the research showcased. We are proud to foster a truly global community, with the majority of published articles originating from outside the United States, reflecting the rapid growth of applied research worldwide.