{"title":"单掩膜 X 射线差分相衬成像的强度传输模型","authors":"Jingcheng Yuan and Mini Das","doi":"10.1364/optica.510537","DOIUrl":null,"url":null,"abstract":"X-ray phase contrast imaging holds great promise for improving the visibility of light-element materials such as soft tissues and tumors. The single-mask differential phase contrast imaging method stands out as a simple and effective approach to yield differential phase contrast. In this work, we introduce a model for a single-mask phase imaging system based on the transport-of-intensity equation. Our model provides an accessible understanding of signal and contrast formation in single-mask x-ray phase imaging, offering a clear perspective on the image formation process, for example, the origin of alternate bright and dark fringes in phase contrast intensity images. Aided by our model, we present an efficient retrieval method that yields differential phase contrast imagery in a single acquisition step. Our model gives insight into the contrast generation and its dependence on the system geometry and imaging parameters in both the initial intensity image as well as retrieved images. The model validity as well as the proposed retrieval method are demonstrated via both experimental results on a system developed in house as well as Monte Carlo simulations. In conclusion, our work not only provides a model for an intuitive visualization of image formation but also offers a method to optimize differential phase imaging setups, holding tremendous promise for advancing medical diagnostics and other applications.","PeriodicalId":19515,"journal":{"name":"Optica","volume":"56 1","pages":""},"PeriodicalIF":8.4000,"publicationDate":"2024-04-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Transport-of-intensity model for single-mask x-ray differential phase contrast imaging\",\"authors\":\"Jingcheng Yuan and Mini Das\",\"doi\":\"10.1364/optica.510537\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"X-ray phase contrast imaging holds great promise for improving the visibility of light-element materials such as soft tissues and tumors. The single-mask differential phase contrast imaging method stands out as a simple and effective approach to yield differential phase contrast. In this work, we introduce a model for a single-mask phase imaging system based on the transport-of-intensity equation. Our model provides an accessible understanding of signal and contrast formation in single-mask x-ray phase imaging, offering a clear perspective on the image formation process, for example, the origin of alternate bright and dark fringes in phase contrast intensity images. Aided by our model, we present an efficient retrieval method that yields differential phase contrast imagery in a single acquisition step. Our model gives insight into the contrast generation and its dependence on the system geometry and imaging parameters in both the initial intensity image as well as retrieved images. The model validity as well as the proposed retrieval method are demonstrated via both experimental results on a system developed in house as well as Monte Carlo simulations. In conclusion, our work not only provides a model for an intuitive visualization of image formation but also offers a method to optimize differential phase imaging setups, holding tremendous promise for advancing medical diagnostics and other applications.\",\"PeriodicalId\":19515,\"journal\":{\"name\":\"Optica\",\"volume\":\"56 1\",\"pages\":\"\"},\"PeriodicalIF\":8.4000,\"publicationDate\":\"2024-04-05\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Optica\",\"FirstCategoryId\":\"101\",\"ListUrlMain\":\"https://doi.org/10.1364/optica.510537\",\"RegionNum\":1,\"RegionCategory\":\"物理与天体物理\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q1\",\"JCRName\":\"OPTICS\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Optica","FirstCategoryId":"101","ListUrlMain":"https://doi.org/10.1364/optica.510537","RegionNum":1,"RegionCategory":"物理与天体物理","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q1","JCRName":"OPTICS","Score":null,"Total":0}
引用次数: 0
摘要
X 射线相衬成像技术在提高软组织和肿瘤等光元素材料的可见度方面大有可为。单掩膜差分相位对比成像法是产生差分相位对比的一种简单而有效的方法。在这项工作中,我们介绍了基于强度传输方程的单掩膜相位成像系统模型。我们的模型提供了对单掩膜 X 射线相位成像中信号和对比度形成的理解,为图像形成过程提供了一个清晰的视角,例如,相位对比强度图像中交替出现的明暗条纹的起源。在模型的帮助下,我们提出了一种高效的检索方法,只需一个采集步骤就能获得不同的相位对比图像。我们的模型深入揭示了对比度的产生及其与初始强度图像和检索图像中的系统几何和成像参数的关系。模型的有效性和所提出的检索方法通过在内部开发的系统上的实验结果和蒙特卡罗模拟得到了证明。总之,我们的工作不仅为图像形成的直观可视化提供了一个模型,还为优化差分相位成像设置提供了一种方法,为推进医疗诊断和其他应用带来了巨大的希望。
Transport-of-intensity model for single-mask x-ray differential phase contrast imaging
X-ray phase contrast imaging holds great promise for improving the visibility of light-element materials such as soft tissues and tumors. The single-mask differential phase contrast imaging method stands out as a simple and effective approach to yield differential phase contrast. In this work, we introduce a model for a single-mask phase imaging system based on the transport-of-intensity equation. Our model provides an accessible understanding of signal and contrast formation in single-mask x-ray phase imaging, offering a clear perspective on the image formation process, for example, the origin of alternate bright and dark fringes in phase contrast intensity images. Aided by our model, we present an efficient retrieval method that yields differential phase contrast imagery in a single acquisition step. Our model gives insight into the contrast generation and its dependence on the system geometry and imaging parameters in both the initial intensity image as well as retrieved images. The model validity as well as the proposed retrieval method are demonstrated via both experimental results on a system developed in house as well as Monte Carlo simulations. In conclusion, our work not only provides a model for an intuitive visualization of image formation but also offers a method to optimize differential phase imaging setups, holding tremendous promise for advancing medical diagnostics and other applications.
期刊介绍:
Optica is an open access, online-only journal published monthly by Optica Publishing Group. It is dedicated to the rapid dissemination of high-impact peer-reviewed research in the field of optics and photonics. The journal provides a forum for theoretical or experimental, fundamental or applied research to be swiftly accessed by the international community. Optica is abstracted and indexed in Chemical Abstracts Service, Current Contents/Physical, Chemical & Earth Sciences, and Science Citation Index Expanded.