孟加拉国成年人的维生素 D 水平及其与高血压发病率的关系。

Mymensingh medical journal : MMJ Pub Date : 2024-04-01
K T Kubra, M A Moni
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摘要

在我国,维生素 D 水平对高血压发病率的影响尚未得到阐明。本研究旨在报告孟加拉国成年人的维生素 D 水平及其与高血压发病率的关系。这项横断面评估在孟加拉国班加班杜-谢赫-穆吉布医科大学(BSMMU)进行,为期一年(2019 年 1 月 1 日至 2019 年 12 月 31 日)。共纳入了 187 名没有已知高血压病史和合并症的参与者。对每位患者进行了维生素 D 检测和高血压风险因素评估。数据收集采用结构化问卷,研究符合现行的赫尔辛基宣言。分析使用 SPSS 26.0 进行。在 187 名参与者中,有 33 人(17.6%)是新诊断出的高血压患者。主要年龄组为 31-40 岁(30.5%),平均发病年龄(±SD)为 36.76±12.14 岁。11.8%、32.6% 和 55.6% 的病例分别存在维生素 D 充足、不足和缺乏的情况。平均(±SD)SBP 和 DBP 分别为 117.41±12.84 和 76.87±9.46 毫米汞柱。男性高血压患者明显多于女性(P=0.047),但维生素 D 与高血压没有关联(P=0.262)。高血压患者和正常血压患者在年龄、性别、体重指数、不健康的饮食习惯、额外的盐摄入量、吸烟、咖啡因摄入量、女性荷尔蒙避孕药等方面都有相似的风险因素(P>0.05)。近五分之一的参与者患有新诊断的高血压,超过五成的参与者缺乏维生素 D。然而,维生素 D 水平与高血压发病率并无统计学意义。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Level of Vitamin D and Its Relation with Incident Hypertension among Bangladeshi Adults.

Effect of vitamin D level on incident hypertension was not elucidated in our country perspective. The objective of the study was to report the level of vitamin D and its relation with incident hypertension among the Bangladeshi adults. This cross-sectional assessment was conducted in Bangabandhu Sheikh Mujib Medical University (BSMMU), Bangladesh for a period of one year (1st January 2019 to 31st December 2019). A total of 187 participants who had no known history of hypertension and comorbidities were included. Vitamin D assay and risk factors assessment for hypertension were performed for each patient. Data collection was done using a structured questionnaire and the study was conducted in compliance with current declaration of Helsinki. Analysis was conducted with SPSS 26.0. Out of 187 participants 33(17.6%) was newly diagnosed with hypertension. Predominant age group was 31-40 years (30.5%) and the average of incidence ±SD was 36.76±12.14 years. Sufficient, insufficient and deficient vitamin D was present in 11.8%, 32.6% and 55.6% cases, respectively. Mean±SD SBP and DBP were 117.41±12.84 and 76.87±9.46 mm of Hg. Hypertension was significantly more common in male than female (p=0.047), but there was no association of vitamin D with hypertension (p=0.262). Both hypertensive and normotensive patients shared similar risk factor profile in terms of age, gender, BMI, unhealthy food habit, extra salt intake, tobacco use, caffeine consumption, hormonal contraceptive of female (p>0.05 for all). Nearly one-fifth participants had newly diagnosed hypertension and more than fifty percent had vitamin D deficiency. However, vitamin D level didn't have any statistically significant association with incident hypertension.

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