癌胚抗原 CEA - 对结直肠癌术后即刻死亡率的预后价值。

Current health sciences journal Pub Date : 2023-10-01 Epub Date: 2023-12-29 DOI:10.12865/CHSJ.49.04.14
Andreea Firut, Sorin Scurtu, Michael Schenker, Nicoleta Gadea, Ana Maria Patrascu, Vlad Padureanu, Stefan Patrascu, Valeriu Surlin
{"title":"癌胚抗原 CEA - 对结直肠癌术后即刻死亡率的预后价值。","authors":"Andreea Firut, Sorin Scurtu, Michael Schenker, Nicoleta Gadea, Ana Maria Patrascu, Vlad Padureanu, Stefan Patrascu, Valeriu Surlin","doi":"10.12865/CHSJ.49.04.14","DOIUrl":null,"url":null,"abstract":"<p><strong>Introduction: </strong>This study investigates the prognostic significance of carcinoembryonic antigen (CEA) levels in predicting early postoperative mortality in patients who have undergone colorectal cancer surgery.</p><p><strong>Methods: </strong>Between 2017 and 2022, total of 325 patients were enrolled in the study, and their preoperative serum CEA levels were measured. Relevant clinical and operative data were extracted and correlations between CEA levels and postoperative mortality was analysed.</p><p><strong>Results: </strong>Among the surgical cases, 180 patients (55.3%) exhibited elevated CEA levels. Within the early postoperative period of 30 days, 14 patients (4.3%) succumbed, comprising 8 cases (2.4%) of colon cancer and 6 cases (1.8%) of rectal cancer. Notably, only 3 cases (0.9%), consisting of 1 (0.3%) colon cancer and 2 (0.6%) rectal cancer cases, were associated with an elevated CEA level. However, no statistically significant correlations were observed between CEA levels and early postoperative mortality.</p><p><strong>Conclusions: </strong>Our findings indicate that increased CEA levels may not serve as a reliable non-invasive marker for identifying patients at high risk of early mortality in the context of colo-rectal cancer surgery.</p>","PeriodicalId":93963,"journal":{"name":"Current health sciences journal","volume":null,"pages":null},"PeriodicalIF":0.0000,"publicationDate":"2023-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10976198/pdf/","citationCount":"0","resultStr":"{\"title\":\"Carcinoembryonic Antigen CEA - Prognostic Value in Immediate Post-Operative Mortality in Colorectal Cancer.\",\"authors\":\"Andreea Firut, Sorin Scurtu, Michael Schenker, Nicoleta Gadea, Ana Maria Patrascu, Vlad Padureanu, Stefan Patrascu, Valeriu Surlin\",\"doi\":\"10.12865/CHSJ.49.04.14\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><strong>Introduction: </strong>This study investigates the prognostic significance of carcinoembryonic antigen (CEA) levels in predicting early postoperative mortality in patients who have undergone colorectal cancer surgery.</p><p><strong>Methods: </strong>Between 2017 and 2022, total of 325 patients were enrolled in the study, and their preoperative serum CEA levels were measured. Relevant clinical and operative data were extracted and correlations between CEA levels and postoperative mortality was analysed.</p><p><strong>Results: </strong>Among the surgical cases, 180 patients (55.3%) exhibited elevated CEA levels. Within the early postoperative period of 30 days, 14 patients (4.3%) succumbed, comprising 8 cases (2.4%) of colon cancer and 6 cases (1.8%) of rectal cancer. Notably, only 3 cases (0.9%), consisting of 1 (0.3%) colon cancer and 2 (0.6%) rectal cancer cases, were associated with an elevated CEA level. However, no statistically significant correlations were observed between CEA levels and early postoperative mortality.</p><p><strong>Conclusions: </strong>Our findings indicate that increased CEA levels may not serve as a reliable non-invasive marker for identifying patients at high risk of early mortality in the context of colo-rectal cancer surgery.</p>\",\"PeriodicalId\":93963,\"journal\":{\"name\":\"Current health sciences journal\",\"volume\":null,\"pages\":null},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2023-10-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10976198/pdf/\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Current health sciences journal\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.12865/CHSJ.49.04.14\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"2023/12/29 0:00:00\",\"PubModel\":\"Epub\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Current health sciences journal","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.12865/CHSJ.49.04.14","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"2023/12/29 0:00:00","PubModel":"Epub","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 0

摘要

简介:本研究探讨了癌胚抗原(CEA)水平对预测结直肠癌手术患者术后早期死亡率的预后意义:本研究探讨了癌胚抗原(CEA)水平在预测结直肠癌手术患者术后早期死亡率方面的预后意义:2017年至2022年间,共有325名患者被纳入研究,并对其术前血清CEA水平进行了测定。提取相关临床和手术数据,分析CEA水平与术后死亡率之间的相关性:结果:在手术病例中,180 名患者(55.3%)的 CEA 水平升高。术后早期 30 天内,有 14 名患者(4.3%)死亡,其中结肠癌 8 例(2.4%),直肠癌 6 例(1.8%)。值得注意的是,只有 3 例(0.9%)患者(包括 1 例(0.3%)结肠癌和 2 例(0.6%)直肠癌)与 CEA 水平升高有关。然而,CEA水平与术后早期死亡率之间没有统计学意义上的相关性:我们的研究结果表明,在结肠直肠癌手术中,CEA水平升高可能并不能作为识别早期死亡高风险患者的可靠非侵入性标志物。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Carcinoembryonic Antigen CEA - Prognostic Value in Immediate Post-Operative Mortality in Colorectal Cancer.

Introduction: This study investigates the prognostic significance of carcinoembryonic antigen (CEA) levels in predicting early postoperative mortality in patients who have undergone colorectal cancer surgery.

Methods: Between 2017 and 2022, total of 325 patients were enrolled in the study, and their preoperative serum CEA levels were measured. Relevant clinical and operative data were extracted and correlations between CEA levels and postoperative mortality was analysed.

Results: Among the surgical cases, 180 patients (55.3%) exhibited elevated CEA levels. Within the early postoperative period of 30 days, 14 patients (4.3%) succumbed, comprising 8 cases (2.4%) of colon cancer and 6 cases (1.8%) of rectal cancer. Notably, only 3 cases (0.9%), consisting of 1 (0.3%) colon cancer and 2 (0.6%) rectal cancer cases, were associated with an elevated CEA level. However, no statistically significant correlations were observed between CEA levels and early postoperative mortality.

Conclusions: Our findings indicate that increased CEA levels may not serve as a reliable non-invasive marker for identifying patients at high risk of early mortality in the context of colo-rectal cancer surgery.

求助全文
通过发布文献求助,成功后即可免费获取论文全文。 去求助
来源期刊
自引率
0.00%
发文量
0
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
确定
请完成安全验证×
copy
已复制链接
快去分享给好友吧!
我知道了
右上角分享
点击右上角分享
0
联系我们:info@booksci.cn Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。 Copyright © 2023 布克学术 All rights reserved.
京ICP备2023020795号-1
ghs 京公网安备 11010802042870号
Book学术文献互助
Book学术文献互助群
群 号:481959085
Book学术官方微信