乳腺癌免疫疗法知识图谱:2013年至2022年的文献计量分析。

IF 4.1 4区 医学 Q2 BIOTECHNOLOGY & APPLIED MICROBIOLOGY
Human Vaccines & Immunotherapeutics Pub Date : 2024-12-31 Epub Date: 2024-04-02 DOI:10.1080/21645515.2024.2335728
Fanli Qu, Guanwen Wang, Ping Wen, Xiaoyu Liu, Xiaohua Zeng
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引用次数: 0

摘要

乳腺癌是全球妇女因癌症死亡的主要原因。免疫疗法已成为当代肿瘤学的一个重要里程碑。本研究旨在对乳腺癌免疫疗法领域进行文献计量分析,全面概述研究现状,确定研究课题的趋势和热点。我们从科学网核心数据库中搜索和检索了数据,并对2013年至2022年有关乳腺癌免疫疗法的出版物进行了文献计量分析。通过使用 VOSviewer 进行共现分析,对现状和热点进行了评估。通过使用 CiteSpace 进行共现分析,评估了知识库的演变和突变。使用 bibliometrix 软件包进行专题演变,以发现关键词趋势。此外,还探讨了国家/地区、机构和作者的归属与合作。共收录了 7975 篇出版物。在关键词共现分析中,发现了 6 个主要群组:肿瘤微环境、预后生物标记物、免疫检查点、新型给药方法、免疫细胞和治疗方法。发表论文最多的国家、机构和作者分别是美国(2926 篇)、德克萨斯大学 MD 安德森癌症中心(219 篇)和 Sherene Loi(28 篇)。世界范围内有关乳腺癌免疫疗法的研究迅速增长。这一研究领域越来越受到不同国家和机构的关注。随着乳腺癌发病率的不断上升,免疫疗法是一个具有重要临床价值和潜力的研究领域。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Knowledge mapping of immunotherapy for breast cancer: A bibliometric analysis from 2013 to 2022.

Breast cancer is the leading cause of cancer-related death among women globally. Immunotherapy has emerged as a major milestone in contemporary oncology. This study aims to conduct a bibliometric analysis in the field of immunotherapy for breast cancer, providing a comprehensive overview of the current research status, identifying trends and hotspots in research topics. We searched and retrieved data from the Web of Science Core Collection, and performed a bibliometric analysis of publications on immunotherapy for breast cancer from 2013 to 2022. Current status and hotspots were evaluated by co-occurrence analysis using VOSviewer. Evolution and bursts of knowledge base were assessed by co-citation analysis using CiteSpace. Thematic evolution by bibliometrix package was used to discover keywords trends. The attribution and collaboration of countries/regions, institutions and authors were also explored. A total of 7,975 publications were included. In co-occurrence analysis of keywords, 6 major clusters were revealed: tumor microenvironment, prognosis biomarker, immune checkpoints, novel drug delivery methods, immune cells and therapeutic approaches. The top three most frequently mentioned keywords were tumor microenvironment, triple-negative breast cancer, and programmed cell death ligand 1. The most productive country, institution and author were the USA (2926 publications), the University of Texas MD Anderson Cancer Center (219 publications), and Sherene Loi (28 publications), respectively. There has been a rapid growth in studies on immunotherapy for breast cancer worldwide. This research area has gained increasing attention from different countries and institutions. With the rising incidence of breast cancer, immunotherapy represents a research field of significant clinical value and potential.

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来源期刊
Human Vaccines & Immunotherapeutics
Human Vaccines & Immunotherapeutics BIOTECHNOLOGY & APPLIED MICROBIOLOGY-IMMUNOLOGY
CiteScore
7.90
自引率
8.30%
发文量
489
审稿时长
3-6 weeks
期刊介绍: (formerly Human Vaccines; issn 1554-8619) Vaccine research and development is extending its reach beyond the prevention of bacterial or viral diseases. There are experimental vaccines for immunotherapeutic purposes and for applications outside of infectious diseases, in diverse fields such as cancer, autoimmunity, allergy, Alzheimer’s and addiction. Many of these vaccines and immunotherapeutics should become available in the next two decades, with consequent benefit for human health. Continued advancement in this field will benefit from a forum that can (A) help to promote interest by keeping investigators updated, and (B) enable an exchange of ideas regarding the latest progress in the many topics pertaining to vaccines and immunotherapeutics. Human Vaccines & Immunotherapeutics provides such a forum. It is published monthly in a format that is accessible to a wide international audience in the academic, industrial and public sectors.
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