用于狗的 eyeTelemed IOPvet 眼压计的验证。

IF 1.7 4区 农林科学 Q2 VETERINARY SCIENCES
Lydia E Kapeller, Ava G Cabble, Phillip N Buckman, Christine D Harman, Amanda L Jacobson, Frank R Lawrence, András M Komáromy
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引用次数: 0

摘要

目的评估 eyeTelemed IOPvet 眼压计估计犬眼压的准确性:第一部分包括 28 只比格犬的 54 只眼睛--23 只患有开角型青光眼的 ADAMTS10 突变体和 5 只正常犬。第二部分包括 5 只正常犬的体外眼球:第 1 部分(体内)将正常犬和青光眼犬的 IOPvet 估计值与 Reichert Tono-Vera® Vet 回弹眼压计进行比较。三种 IOPvet 估计值均为绿色(正常;30 毫米汞柱)。在第二部分(体外)中,新鲜去核正常犬眼内的压力从 5 mmHg 逐步增加到 80 mmHg,并与 IOPvet 估计值进行比较。将 IOPvet 估计值与反弹眼压计和直接测压法进行了描述性统计比较,将从正常到青光眼的阈值设定为 30 毫米汞柱:在第一部分(活体)中,正常压力(≤30 mmHg)主要被正确识别为绿色或黄色--111 个估计值中有 110 个被正确识别为绿色或黄色,特异性为 99%。在 125 个受影响的估计值中,只有 16 个正确显示在 >30 mmHg 范围内;其余 109 个显示≤30 mmHg,灵敏度为 13%。在第 2 部分(体外)中,所有正常压力的绿色估计值都是正确的,但 88 个人工测量的 IOP >30 mmHg 中,有 64 个被错误地估计为 20-30 mmHg:结论:IOPvet 估算犬类眼压不准确,识别眼压大于 30 mmHg 的犬的灵敏度较低。要正确识别眼压升高(黄色 = 20-30 mmHg)和眼压过高(红色 >30 mmHg),需要对针对犬类的仪器进行修订。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Validation of the eyeTelemed IOPvet indentation tonometer for use in dogs.

Objective: To assess the accuracy of canine intraocular pressure (IOP) estimates from the eyeTelemed IOPvet indentation tonometer.

Animals studied: Part 1 included 54 eyes from 28 Beagle dogs-23 ADAMTS10-mutants with open-angle glaucoma and 5 normals. Part 2 involved five normal canine ex vivo globes.

Procedure: Part 1 (in vivo) compared IOPvet estimates in normal and glaucomatous dogs to Reichert Tono-Vera® Vet rebound tonometry. The three IOPvet estimates were green (normal; <20 mmHg, according to the manufacturer), yellow (elevated; 20-30 mmHg), and red (high; >30 mmHg). In Part 2 (ex vivo), the pressure inside freshly enucleated normal canine eyes was progressively increased from 5 to 80 mmHg and compared to IOPvet estimates. Descriptive statistics compared IOPvet estimates to rebound tonometry and direct manometry, with the threshold from normal to glaucoma set at 30 mmHg.

Results: In Part 1 (in vivo), normal pressures (≤30 mmHg) were mainly identified correctly as green or yellow-110 of 111 estimates, corresponding to a specificity of 99%. Only 16 of 125 affected estimates were correctly displayed in the >30-mmHg range; the remaining 109 showed ≤30 mmHg, corresponding to a sensitivity of 13%. In Part 2 (ex vivo), all normal pressures were correctly estimated with green, but 64 of 88 manometric IOPs >30 mmHg were falsely estimated as 20-30 mmHg.

Conclusions: The IOPvet is inaccurate in estimating canine IOP with a low sensitivity at identifying dogs with IOP > 30 mmHg. Canine-specific instrument revision is required to correctly identify elevated (yellow = 20-30 mmHg) and high (red >30 mmHg) IOPs.

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来源期刊
Veterinary ophthalmology
Veterinary ophthalmology 农林科学-兽医学
CiteScore
2.70
自引率
37.50%
发文量
82
审稿时长
12-24 weeks
期刊介绍: Veterinary Ophthalmology is a peer-reviewed, international journal that welcomes submission of manuscripts directed towards academic researchers of veterinary ophthalmology, specialists and general practitioners with a strong ophthalmology interest. Articles include those relating to all aspects of: Clinical and investigational veterinary and comparative ophthalmology; Prospective and retrospective studies or reviews of naturally occurring ocular disease in veterinary species; Experimental models of both animal and human ocular disease in veterinary species; Anatomic studies of the animal eye; Physiological studies of the animal eye; Pharmacological studies of the animal eye.
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