使用延迟全肝切除术(RAPID)进行肝硬化患者左叶活体肝移植:韩国首例报告。

IF 1.1 Q4 GASTROENTEROLOGY & HEPATOLOGY
Annals of hepato-biliary-pancreatic surgery Pub Date : 2024-08-31 Epub Date: 2024-04-01 DOI:10.14701/ahbps.24-005
Jongman Kim, Jinsoo Rhu, Eunjin Lee, Youngju Ryu, Sunghyo An, Sung Jun Jo, Namkee Oh, Seungwook Han, Sunghae Park, Gyu-Seong Choi
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引用次数: 0

摘要

在肝脏移植手术中,首要问题是确保供体未来有足够的肝脏残余(FLR),同时为受体选择足够大小的移植物。活体肝移植(LDLT)中的活体供体切除和部分肝段2-3移植延迟全肝切除术(LD-RAPID)为扩大供体库提供了一个潜在的解决方案。我们报告了第一例使用LD-RAPID程序进行左叶LDLT的肝硬化患者,患者患有自身免疫性肝炎和肝细胞癌。活体肝脏捐献者(LLD)接受了腹腔镜左肝切除术,包括肝中静脉。受体一侧的切除术是扩大的左肝切除术,包括肝中静脉口和尾状叶。术后第 7 天,计算机断层扫描显示左侧移植物从 320 克肥大到 465 毫升(即移植物体积体重比从 0.60% 增加到 0.77%,增加了 45.3%)。间隔 7 天后,在第二阶段手术中切除病变右叶。使用左叶移植物的LD-RAPID手术允许在LDLT中使用小肝脏移植物或小体积的LLD FLR,这扩大了供体库,通过捐献较小的肝脏部分,将LLD的风险降至最低。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Left lobe living donor liver transplantation using the resection and partial liver segment 2-3 transplantation with delayed total hepatectomy (RAPID) procedure in cirrhotic patients: First case report in Korea.

In liver transplantation, the primary concern is to ensure an adequate future liver remnant (FLR) volume for the donor, while selecting a graft of sufficient size for the recipient. The living donor-resection and partial liver segment 2-3 transplantation with delayed total hepatectomy (LD-RAPID) procedure offers a potential solution to expand the donor pool for living donor liver transplantation (LDLT). We report the first case involving a cirrhotic patient with autoimmune hepatitis and hepatocellular carcinoma, who underwent left lobe LDLT using the LD-RAPID procedure. The living liver donor (LLD) underwent a laparoscopic left hepatectomy, including middle hepatic vein. The resection on the recipient side was an extended left hepatectomy, including the middle hepatic vein orifice and caudate lobe. At postoperative day 7, a computed tomography scan showed hypertrophy of the left graft from 320 g to 465 mL (i.e., a 45.3% increase in graft volume body weight ratio from 0.60% to 0.77%). After a 7-day interval, the diseased right lobe was removed in the second stage surgery. The LD-RAPID procedure using left lobe graft allows for the use of a small liver graft or small FLR volume in LLD in LDLT, which expands the donor pool to minimize the risk to LLD by enabling the donation of a smaller liver portion.

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