在重症监护室使用抗精神病药物治疗谵妄不会导致 QTc 间期延长

The Brown University Psychopharmacology Update Pub Date : 2024-03-29 DOI:10.1002/pu.31155

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引用次数: 0

摘要

一项随机试验的二次分析发现，在重症监护期间接受氟哌啶醇或齐拉西酮治疗谵妄的住院病人与安慰剂相比，QTc间期延长的风险并没有增加。接受其中一种抗精神病药物治疗的患者发生的少量心脏事件均未被确定与研究用药有关。

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Antipsychotics for delirium in ICU did not result in QTc interval prolongation

Hospitalized patients receiving haloperidol or ziprasidone for delirium while in intensive care experienced no increased risk of QTc interval prolongation relative to placebo, a secondary analysis of a randomized trial has found. None of the small number of cardiac events experienced by patients receiving one of the antipsychotics were determined to be associated with study drug administration.

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The Brown University Psychopharmacology Update

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