阿根廷布宜诺斯艾利斯市医护人员接种 Covid-19 疫苗的有效性和安全性。

Q3 Medicine
Vanina Pagotto, Facundo Seoane, Diego Arrigo, Victoria Ardiles, Valeria Asprea, Florencia De Florio, Analia Ferloni, Valeria Aliperti
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引用次数: 0

摘要

接种 COVID-19 疫苗有助于限制大流行。阿根廷批准了三种疫苗,并优先考虑医护人员 (HCW)。目的是通过分析免疫球蛋白 G 水平的变化和接种第二剂后 12 个月内 COVID-19 新病例的发生率,确定 COVID-19 疫苗的有效性。方法:对 2021 年 3 月至 2022 年期间的 TDS 进行前瞻性队列研究。使用 COVIDAR IgG 测试测量抗体。使用混合效应模型比较不同时间点的免疫球蛋白 G 水平,使用 Kaplan Meier 估计 COVID-19 的发病情况。结果:共纳入 82 名参与者。不良反应频繁但轻微。所有参与者在 12 个月时抗体均呈阳性。第二剂后一年,抗体水平有所上升。国药集团用了很长时间才显示出阳性结果。超过一半的人患有轻微的 COVID-19 疾病。结论:COVID-19 疫苗安全有效。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
[Effectiveness and safety of COVID-19 vaccines in healthcare workers in Buenos Aires City, Argentina.]

Introduction: COVID-19 vaccination aids pandemic limitation. In Argentina, three vaccines are approved, and healthcare workers are priorized (HCWs). The aim was to determine the effectiveness of COVID-19 vaccines, analyzing change in Immunoglobulin G levels and the incidence of new COVID-19 cases up to 12 months after the second dose.

Methods: Prospective cohort of HCWs between March 2021- 2022. COVIDAR IgG test was used to measure antibodies. A mixed-effects model was employed to compare the levels of immunoglobulin G at different time points, Kaplan Meier was used to estimate incident COVID-19 cases.

Results: 82 participants were included Adverse events were frequent but mild. All participant showed positive antibody at 12 months. Antibodies levels showed an increase one year after 2nd dose. Sinopharm took a long time to yield positive results. More than half of the people had mild COVID-19 disease.

Conclusion: COVID-19 vaccines are safe and effective.

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来源期刊
CiteScore
1.60
自引率
0.00%
发文量
60
审稿时长
20 weeks
期刊介绍: The Journal of the Faculty of Medical Sciences is a scientific publication of the Secretariat of Science and Technology of the Faculty of Medical Sciences of the National University of Cordoba. Its objective is to disseminate and promote research work related to Medical and Biological Sciences. It publishes scientific works of national and international professionals on different topics related to health sciences from the field of medicine, nursing, kinesiology, diagnostic imaging, phonoaudiology, nutrition, public health, chemical sciences, dentistry and related.
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