An Qi Xu, Nicolas Nguyen, Elie Bou Assi, Dang Khoa Nguyen
{"title":"刺激扣带回运动","authors":"An Qi Xu, Nicolas Nguyen, Elie Bou Assi, Dang Khoa Nguyen","doi":"10.1002/epd2.20219","DOIUrl":null,"url":null,"abstract":"<p>Locomotion is a goal-oriented behavior divided into three components: initiation (volitional or emotional), rhythmic limb movements, and intentional adjustment.<span><sup>1</sup></span> Volitional initiation involves the frontal cortex and thalamus, guided by an individual's intention to move<span><sup>2-4</sup></span>. Emotional initiation is directed by the cingulate cortex and insula, leading to a sensation of urge to move. After initiation of the locomotion, rhythmic limb movements are coordinated by central pattern generators in the brainstem, spinal cord, and cerebellum.<span><sup>4</sup></span> Our patient, a 45-year-old male who underwent an intracranial EEG study for left frontal lobe epilepsy, electrical stimulation of the anterior midcingulate cortex at 6 mA for 5 seconds repeatedly induced an “urge to move” and initiated a “getting-up” motion (Video 1), similar to the findings of Jackson et al.<span><sup>1</sup></span> and Caruana et al.<span><sup>5</sup></span></p>","PeriodicalId":1,"journal":{"name":"Accounts of Chemical Research","volume":null,"pages":null},"PeriodicalIF":16.4000,"publicationDate":"2024-03-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/epd2.20219","citationCount":"0","resultStr":"{\"title\":\"Stimulating the cingulate to move\",\"authors\":\"An Qi Xu, Nicolas Nguyen, Elie Bou Assi, Dang Khoa Nguyen\",\"doi\":\"10.1002/epd2.20219\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p>Locomotion is a goal-oriented behavior divided into three components: initiation (volitional or emotional), rhythmic limb movements, and intentional adjustment.<span><sup>1</sup></span> Volitional initiation involves the frontal cortex and thalamus, guided by an individual's intention to move<span><sup>2-4</sup></span>. Emotional initiation is directed by the cingulate cortex and insula, leading to a sensation of urge to move. After initiation of the locomotion, rhythmic limb movements are coordinated by central pattern generators in the brainstem, spinal cord, and cerebellum.<span><sup>4</sup></span> Our patient, a 45-year-old male who underwent an intracranial EEG study for left frontal lobe epilepsy, electrical stimulation of the anterior midcingulate cortex at 6 mA for 5 seconds repeatedly induced an “urge to move” and initiated a “getting-up” motion (Video 1), similar to the findings of Jackson et al.<span><sup>1</sup></span> and Caruana et al.<span><sup>5</sup></span></p>\",\"PeriodicalId\":1,\"journal\":{\"name\":\"Accounts of Chemical Research\",\"volume\":null,\"pages\":null},\"PeriodicalIF\":16.4000,\"publicationDate\":\"2024-03-27\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://onlinelibrary.wiley.com/doi/epdf/10.1002/epd2.20219\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Accounts of Chemical Research\",\"FirstCategoryId\":\"3\",\"ListUrlMain\":\"https://onlinelibrary.wiley.com/doi/10.1002/epd2.20219\",\"RegionNum\":1,\"RegionCategory\":\"化学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q1\",\"JCRName\":\"CHEMISTRY, MULTIDISCIPLINARY\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Accounts of Chemical Research","FirstCategoryId":"3","ListUrlMain":"https://onlinelibrary.wiley.com/doi/10.1002/epd2.20219","RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q1","JCRName":"CHEMISTRY, MULTIDISCIPLINARY","Score":null,"Total":0}
Locomotion is a goal-oriented behavior divided into three components: initiation (volitional or emotional), rhythmic limb movements, and intentional adjustment.1 Volitional initiation involves the frontal cortex and thalamus, guided by an individual's intention to move2-4. Emotional initiation is directed by the cingulate cortex and insula, leading to a sensation of urge to move. After initiation of the locomotion, rhythmic limb movements are coordinated by central pattern generators in the brainstem, spinal cord, and cerebellum.4 Our patient, a 45-year-old male who underwent an intracranial EEG study for left frontal lobe epilepsy, electrical stimulation of the anterior midcingulate cortex at 6 mA for 5 seconds repeatedly induced an “urge to move” and initiated a “getting-up” motion (Video 1), similar to the findings of Jackson et al.1 and Caruana et al.5
期刊介绍：
Accounts of Chemical Research presents short, concise and critical articles offering easy-to-read overviews of basic research and applications in all areas of chemistry and biochemistry. These short reviews focus on research from the author’s own laboratory and are designed to teach the reader about a research project. In addition, Accounts of Chemical Research publishes commentaries that give an informed opinion on a current research problem. Special Issues online are devoted to a single topic of unusual activity and significance.
Accounts of Chemical Research replaces the traditional article abstract with an article "Conspectus." These entries synopsize the research affording the reader a closer look at the content and significance of an article. Through this provision of a more detailed description of the article contents, the Conspectus enhances the article's discoverability by search engines and the exposure for the research.
求助内容：
应助结果提醒方式：
京公网安备 11010802042870号
