特殊人群的转移性黑色素瘤治疗。

IF 2.6 4区医学 Q3 ONCOLOGY

Cancer journal Pub Date : 2024-03-01 DOI:10.1097/PPO.0000000000000701

Madeline Miceli, Christina Boatwright, Janice M Mehnert

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引用次数: 0

摘要

摘要：本综述概述了最新的转移性黑色素瘤治疗建议，以及实体器官移植患者、肾功能不全患者和原有自身免疫性疾病患者的相关风险。最初的临床试验研究了晚期黑色素瘤环境中的免疫检查点抑制剂和BRAF/MEK抑制剂，但这些特定治疗人群被排除在外。我们综合了目前的文献，主要是病例系列和回顾性分析，以反映目前治疗这些特殊患者群体的证据。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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Metastatic Melanoma Treatment in Special Populations.

Abstract: This review outlines the most up-to-date metastatic melanoma treatment recommendations and relevant risks for patients with solid organ transplants, patients with renal dysfunction, and patients with preexisting autoimmune conditions. These specific treatment populations were excluded from the original clinical trials, which studied immune checkpoint inhibitors and BRAF/MEK inhibitors in the advanced melanoma setting. We have synthesized the current body of literature, mainly case series and retrospective analyses, to reflect the evidence for the treatment of these special patient populations at present.

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来源期刊

Cancer journal 医学-肿瘤学

CiteScore

3.90

自引率

0.00%

发文量

102

审稿时长

7.5 months

期刊介绍： The Cancer Journal: The Journal of Principles & Practice of Oncology provides an integrated view of modern oncology across all disciplines. The Journal publishes original research and reviews, and keeps readers current on content published in the book Cancer: Principles & Practice of Oncology.