用于软骨和骨软骨损伤的无细胞仿生支架:定制和标准化植入手术技术

Luca Andriolo , Luca De Marziani , Alessandro Di Martino , Angelo Boffa , Stefano Zaffagnini , Giuseppe Filardo
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引用次数: 0

摘要

导言无细胞软骨和骨软骨支架已被用于治疗关节表面的病变。正确的植入技术是有利于支架整合、再生过程和积极临床结果的关键。本文旨在描述定制的传统徒手植入方法和创新的微创技术的适应症和手术步骤,以标准化植入这种仿生无细胞支架(MaioRegen;Fin-Ceramica Faenza Spa)。方法提供了这种支架植入的适应症和禁忌症。方法介绍了这种支架植入术的适应症和禁忌症,还描述了手术准备、植入技术和术后管理的必要步骤,以解决膝关节表面的病变。结果开发出了一种用于不同尺寸圆形植入物的专用器械,可以更精确地准备缺损的深度和宽度,减少创口并增加植入物的稳定性。当病变不允许使用标准化器械技术时,使用凿子和截骨刀的定制徒手技术仍然有用。结论 通过指导读者掌握围手术期和术中的关键步骤,可以使用无细胞支架治疗软骨和骨软骨缺损,最大限度地提高植入物的稳定性。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Cell-free biomimetic scaffold for chondral and osteochondral lesions: surgical technique for custom and standardized implantation

Introduction

Cell-free chondral and osteochondral scaffolds have been introduced to address lesions of the articular surface. A proper implantation technique is key to favor scaffold integration, regenerative processes, and positive clinical outcomes.

Objectives

The purpose of this article is to describe indications and surgical steps for both the custom traditional free-hand implantation approach and an innovative minimally invasive technique for the standardized implantation of this biomimetic cell-free scaffold (MaioRegen; Fin-Ceramica Faenza Spa).

Methods

Indications and contraindications for this scaffold implantation have been provided. The required steps for surgical preparation, implantation technique, and postoperative management have been described as well to address articular surface lesions of the knee.

Results

A dedicated instrumentation for circular implants of different sizes has been developed to allow more precise preparation of the depth and width of the defect, reducing the invasiveness and increasing implant stability. The custom free-hand technique with chisels and osteotomes remains useful when the lesion does not allow the use of the standardized instrumented technique. In case further stability of the implant is needed, fibrin glue addition should be considered.

Conclusions

By guiding the readers with the key perioperative and intraoperative steps, chondral and osteochondral defects can be addressed with the use of a cell-free scaffold, maximizing implant stability.

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