乳腺癌管理:营养、运动和社会心理健康的作用

Sankar Jyoti Bora, D. J. Deka, Chinmoy Malakar, Nancy Kashyap, Bhrigu Kumar Das
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引用次数: 0

摘要

全世界的乳腺癌发病率和死亡率都在上升,这对妇女来说是一个严峻的挑战。靶向药物疗法的发展为治疗提供了前景广阔的途径,但由于资源限制,这些疗法无法在先进的临床试验中得到广泛应用,这凸显了对持续研究资金的需求。营养支持在癌症治疗中至关重要,会影响癌症的主要特征。运动和健康饮食的抗炎作用对于降低癌症发病率和减少肿瘤生长至关重要。本研究对乳腺癌、营养、体育锻炼、社会心理问题、临床试验/研究、机制、体外和体内等方面进行了全面的文献检索。研究使用了多个搜索引擎和主要关键词进行检索,仅收录了截至 2023 年 8 月的英文出版物。鉴于全球乳腺癌挑战日益严峻,我们的研究强调了加强临床试验的可用性、探索营养与癌症之间的联系以及改进心理干预措施以全面解决预防和治疗问题的迫切需要。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Breast Cancer Management: The Role of Nutrition, Exercise and Psychosocial Well-being
Breast cancer incidence and mortality rates are rising worldwide, which presents a formidable challenge for women. The advancement of targeted drug therapies offers promising avenues for treatment, but resource constraints prevent their widespread implementation in advanced clinical trials, highlighting the need for sustained research funding. Nutritional support is critical in cancer management, affecting key cancer hallmarks. The anti-inflammatory effects of exercise and a healthy diet are critical in reducing cancer incidence and tumor growth. A comprehensive approach to breast cancer treatment requires addressing health challenges and psychological symptoms. In this context, we aim to address modifiable risk factors, including nutrition, physical activity, and psychosocial factors, which can serve as non-pharmacological adjuncts in reducing breast cancer risk, incidence, and mortality. This study conducted a thorough literature search on breast cancer, nutrition, physical activity, psychosocial problems, clinical trial/study, mechanisms, in-vitro and in-vivo. The search was performed using multiple search engines and the main keywords, and only English publications until August 2023 were included. Nutrition plays a critical role in influencing breast cancer risk, but its exact role needs to be explored. Diet diversity and exercise are recommended to reduce risk, while psychosocial support is vital for patient well-being. In light of rising global breast cancer challenges, our study underscores the urgent need for enhanced clinical trial availability, exploration of nutrition-cancer links, and refined psychosocial interventions to comprehensively address prevention and treatment.
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