化学传感器的合成与表征：氰化物传感调查和活细胞成像研究

IF 16.4 1区化学 Q1 CHEMISTRY, MULTIDISCIPLINARY

Accounts of Chemical Research Pub Date : 2024-03-15 DOI:10.3233/mgc-240001

Shiva Arun, A. K. Tripathi, Puspendra Singh

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引用次数: 0

摘要

化学传感器 A ，(E)-(4-(2-((2-羟基萘-1-基)亚甲基)肼基)苯腈是由 4-氰基苯肼盐酸盐与 2-羟基-1-萘甲醛在乙醇溶剂中于 ∼80°C 缩合合成的。化学传感器 A 已通过 FT-IR、ESI-MS 和 1H-NMR 光谱技术进行了表征。通过紫外可见光谱和荧光光谱研究了化学传感器 A 对氰离子的选择性感应能力。此外，化学传感器 A 还被用作活细胞成像试剂，用于 SW480 细胞中氰离子的细胞内检测。

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Synthesis and characterization of chemosensor: Investigation of cyanide sensing and study as live cell imaging

Chemosensor A , (E)-(4-(2-((2-hydroxynaphthalene-1-yl)methylene)hydrazinyl)benzonitrile has been synthesized by condensation of 4-cyanophenylhydrazine hydrochloride with 2-hydroxy-1-naphthaldehyde in ethanol solvent at ∼80°C. The chemosensor A , has been characterized by FT-IR, ESI-MS and 1H-NMR spectroscopic techniques. The chemosensor A has been investigated for selective cyanide ion sensing ability through UV–visible and fluorescence spectra. Further the chemosensor A was also employed as live cell imaging reagent for intra-cellular detection of cyanide ion in SW480 cells.

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来源期刊

Accounts of Chemical Research 化学-化学综合

CiteScore

31.40

自引率

1.10%

发文量

312

审稿时长

2 months

期刊介绍： Accounts of Chemical Research presents short, concise and critical articles offering easy-to-read overviews of basic research and applications in all areas of chemistry and biochemistry. These short reviews focus on research from the author’s own laboratory and are designed to teach the reader about a research project. In addition, Accounts of Chemical Research publishes commentaries that give an informed opinion on a current research problem. Special Issues online are devoted to a single topic of unusual activity and significance. Accounts of Chemical Research replaces the traditional article abstract with an article "Conspectus." These entries synopsize the research affording the reader a closer look at the content and significance of an article. Through this provision of a more detailed description of the article contents, the Conspectus enhances the article's discoverability by search engines and the exposure for the research.