针灸治疗深部浸润性子宫内膜异位症的疼痛和与疼痛相关的残疾。

IF 2.5 Q2 CLINICAL NEUROLOGY
Frontiers in pain research (Lausanne, Switzerland) Pub Date : 2024-03-08 eCollection Date: 2024-01-01 DOI:10.3389/fpain.2024.1279312
Giulia Chiarle, Gianni Allais, Silvia Sinigaglia, Gisella Airola, Sara Rolando, Fabiola Bergandi, Salvatore Micalef, Chiara Benedetto
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引用次数: 0

摘要

研究目的评估针灸在缓解深部浸润性子宫内膜异位症(DIE)患者症状(痛经、排便困难、盆腔疼痛和月经失调)强度、改善功能障碍、减少痛经月天数、镇痛剂使用频率和疗效方面的疗效。此外,还对其安全性进行了评估:研究样本为 34 名 DIE 患者;在两个月的时间里(T-2、T-1),妇女们记录了月经天数、痛经、排便困难、盆腔疼痛和月经失调的存在、强度和残疾情况。然后,她们在 6 个月内共接受了 15 次针灸治疗(T1-T6;每周一次,共 12 周,然后每月一次,共 3 个月):结果:治疗期间痛经的强度有所降低。从 T1 到 T6,58.6% 的患者痛经天数至少减少了 50%,中度至重度残疾程度有所减轻。痛经强度从 T2 开始稳步下降;中度至重度残疾妇女的比例从 T2 的 73.3%下降到 T3、T4 和 T5 的 36.9%。盆腔疼痛评分从 T1 开始下降;残疾比例从 T2 的 83.3% 下降到 T3 和 T6 的 33.3%。排便困难的程度从 T-2 到 T3 和 T4 有所减轻,然后略有加重。治疗期间镇痛药的用量较少,疗效似乎更好:尽管存在局限性,但我们的研究结果表明,针灸在减轻疼痛强度和症状相关残疾方面是安全有效的。需要进行更大规模的研究,以比较针灸和药物疗法对子宫内膜异位症相关疼痛的治疗效果。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Acupuncture for pain and pain-related disability in deep infiltrating endometriosis.

Objectives: To evaluate the efficacy of acupuncture in relieving symptoms (dysmenorrhea, dyspareunia, pelvic pain and dyschezia) intensity, improving functional disability, reducing the number of days per months of dysmenorrhea, the frequency and the efficacy of analgesic use in deep infiltrating endometriosis (DIE). The safety profile was also evaluated.

Methods: The study sample was 34 patients with DIE; for 2 months (T-2, T-1) the women recorded diary notes on the numbers of days of menstruation, the presence, intensity, and disability related to dysmenorrhea, dyspareunia, pelvic pain, and dyschezia. They then received a total of 15 acupuncture treatments over 6 months (T1-T6; once a week for 12 weeks, then once a month for 3 months).

Results: Dysmenorrhea intensity was decreased during treatment. A decrease of at least 50% in number of days of dysmenorrhea, and a decrease in moderate-to-severe disability starting from T1 to T6 was recorded for 58.6% of patients. Dyspareunia intensity steadily decreased starting at T2; the percentage of women with moderate-to-severe disability declined from 73.3% at T-2, to 36.9% at T3, T4, and T5. A decrease in pelvic pain score was noted starting at T1; the percentage of disability decreased from 83.3% at T-2 to 33.3% at T3 and T6. The intensity of dyschezia decreased from T-2 to T3 and T4 and then increased slightly. Analgesic drug use was lower during treatment and its efficacy appeared to be greater.

Conclusions: The limitations notwithstanding our study-findings show that acupuncture was safe and effective in reducing pain intensity and symptoms-related disability. Larger-scale studies are needed to compare acupuncture and pharmacotherapy for endometriosis-related pain.

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