{"title":"修改毛细管数量,使抽吸驱动微流控技术中的液滴生成标准化","authors":"Jatin Panwar, Rahul Roy","doi":"10.1007/s10404-024-02714-2","DOIUrl":null,"url":null,"abstract":"<div><p>In droplet microfluidic devices with suction-based flow control, the microchannel geometry and suction pressure at the outlet govern the dynamic properties of the two phases that influence the droplet generation. Therefore, it is critical to understand the role of geometry along with suction pressure in the dynamics of droplet generation to develop a predictive model. We conducted a comprehensive characterization of droplet generation in a flow focusing device with varying control parameters. We used these results to formulate a scaling argument and propose a governing parameter, called as modified capillary number (Ca<sub>L</sub>), that combines normalized droplet volume with geometrical parameters (length of dispersed and continuous phase channels) and flow parameters (interfacial tension, phase viscosity and velocity) in a power law relationship. Ca<sub>L</sub> effectively captures the transition from squeezing to dripping regimes of droplet generation, providing essential insights into the design requirements for suction-driven droplet generation. These findings are key to standardize microfluidic flow-focusing devices that can achieve the desired droplet generation behavior with optimal pressure consumption.</p></div>","PeriodicalId":706,"journal":{"name":"Microfluidics and Nanofluidics","volume":null,"pages":null},"PeriodicalIF":2.3000,"publicationDate":"2024-03-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Modified capillary number to standardize droplet generation in suction-driven microfluidics\",\"authors\":\"Jatin Panwar, Rahul Roy\",\"doi\":\"10.1007/s10404-024-02714-2\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<div><p>In droplet microfluidic devices with suction-based flow control, the microchannel geometry and suction pressure at the outlet govern the dynamic properties of the two phases that influence the droplet generation. Therefore, it is critical to understand the role of geometry along with suction pressure in the dynamics of droplet generation to develop a predictive model. We conducted a comprehensive characterization of droplet generation in a flow focusing device with varying control parameters. We used these results to formulate a scaling argument and propose a governing parameter, called as modified capillary number (Ca<sub>L</sub>), that combines normalized droplet volume with geometrical parameters (length of dispersed and continuous phase channels) and flow parameters (interfacial tension, phase viscosity and velocity) in a power law relationship. Ca<sub>L</sub> effectively captures the transition from squeezing to dripping regimes of droplet generation, providing essential insights into the design requirements for suction-driven droplet generation. These findings are key to standardize microfluidic flow-focusing devices that can achieve the desired droplet generation behavior with optimal pressure consumption.</p></div>\",\"PeriodicalId\":706,\"journal\":{\"name\":\"Microfluidics and Nanofluidics\",\"volume\":null,\"pages\":null},\"PeriodicalIF\":2.3000,\"publicationDate\":\"2024-03-22\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Microfluidics and Nanofluidics\",\"FirstCategoryId\":\"5\",\"ListUrlMain\":\"https://link.springer.com/article/10.1007/s10404-024-02714-2\",\"RegionNum\":4,\"RegionCategory\":\"工程技术\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q2\",\"JCRName\":\"INSTRUMENTS & INSTRUMENTATION\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Microfluidics and Nanofluidics","FirstCategoryId":"5","ListUrlMain":"https://link.springer.com/article/10.1007/s10404-024-02714-2","RegionNum":4,"RegionCategory":"工程技术","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q2","JCRName":"INSTRUMENTS & INSTRUMENTATION","Score":null,"Total":0}
Modified capillary number to standardize droplet generation in suction-driven microfluidics
In droplet microfluidic devices with suction-based flow control, the microchannel geometry and suction pressure at the outlet govern the dynamic properties of the two phases that influence the droplet generation. Therefore, it is critical to understand the role of geometry along with suction pressure in the dynamics of droplet generation to develop a predictive model. We conducted a comprehensive characterization of droplet generation in a flow focusing device with varying control parameters. We used these results to formulate a scaling argument and propose a governing parameter, called as modified capillary number (CaL), that combines normalized droplet volume with geometrical parameters (length of dispersed and continuous phase channels) and flow parameters (interfacial tension, phase viscosity and velocity) in a power law relationship. CaL effectively captures the transition from squeezing to dripping regimes of droplet generation, providing essential insights into the design requirements for suction-driven droplet generation. These findings are key to standardize microfluidic flow-focusing devices that can achieve the desired droplet generation behavior with optimal pressure consumption.
期刊介绍:
Microfluidics and Nanofluidics is an international peer-reviewed journal that aims to publish papers in all aspects of microfluidics, nanofluidics and lab-on-a-chip science and technology. The objectives of the journal are to (1) provide an overview of the current state of the research and development in microfluidics, nanofluidics and lab-on-a-chip devices, (2) improve the fundamental understanding of microfluidic and nanofluidic phenomena, and (3) discuss applications of microfluidics, nanofluidics and lab-on-a-chip devices. Topics covered in this journal include:
1.000 Fundamental principles of micro- and nanoscale phenomena like,
flow, mass transport and reactions
3.000 Theoretical models and numerical simulation with experimental and/or analytical proof
4.000 Novel measurement & characterization technologies
5.000 Devices (actuators and sensors)
6.000 New unit-operations for dedicated microfluidic platforms
7.000 Lab-on-a-Chip applications
8.000 Microfabrication technologies and materials
Please note, Microfluidics and Nanofluidics does not publish manuscripts studying pure microscale heat transfer since there are many journals that cover this field of research (Journal of Heat Transfer, Journal of Heat and Mass Transfer, Journal of Heat and Fluid Flow, etc.).