五肽成分对其稳定性影响的概率评估

IF 0.6 4区计算机科学 Q4 AUTOMATION & CONTROL SYSTEMS

Automation and Remote Control Pub Date : 2024-03-21 DOI:10.1134/S0005117923120032

A. I. Mikhalskii, J. A. Novoseltseva, A. A. Anashkina, A. N. Nekrasov

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引用次数: 0

摘要

摘要正在研究五肽中氨基酸残基的排列对其稳定性的影响。利用梯度提升法对五肽的稳定性进行了预测，从而评估了每个特征对五肽稳定性的影响。研究发现，五肽中的氨基酸排列组合对其稳定性有重要影响。研究表明，使用这些组合可以减少可靠预测五肽稳定性所需的数据量。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

Probabilistic Assessment of a Pentapeptide Composition Influence on Its Stability

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Probabilistic Assessment of a Pentapeptide Composition Influence on Its Stability

The influence of the arrangement of amino acid residues in a pentapeptide on its stability is being studied. A forecast of pentapeptide stability is made using the gradient boosting method, which allows one to evaluate the influence of each feature on the stability of the pentapeptide. Combinations of amino acid arrangements in the pentapeptide have been identified that make a significant contribution to its stability. It has been shown that the use of such combinations reduces the amount of data required to obtain a reliable prediction of pentapeptide stability.

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来源期刊

Automation and Remote Control 工程技术-仪器仪表

CiteScore

1.70

自引率

28.60%

发文量

审稿时长

3-8 weeks

期刊介绍： Automation and Remote Control is one of the first journals on control theory. The scope of the journal is control theory problems and applications. The journal publishes reviews, original articles, and short communications (deterministic, stochastic, adaptive, and robust formulations) and its applications (computer control, components and instruments, process control, social and economy control, etc.).