TBAB 催化对位醌甲化物的 1,6-共轭重氮化反应：获得多取代α-重氮羰基化合物的有效途径

IF 5.8 2区化学 Q1 CHEMISTRY, MULTIDISCIPLINARY

Journal of Saudi Chemical Society Pub Date : 2024-03-20 DOI:10.1016/j.jscs.2024.101846

Zhang-Qin Liu, Sheng-Shu Liu, Xiao-Yu Guan

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引用次数: 0

摘要

通过溴化四丁基铵（TBAB）催化的 1,6 共轭加成途径，建立了重氮乙酸酯与对醌甲酯的高效重氮化反应。该方法提供了一种方便、安全和快速的途径来生成多种多取代的 α-重氮羰基化合物，具有良好的官能团耐受性、高原子经济性和易得性。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

TBAB-catalyzed 1,6-conjugate diazotization of para-quinone methides: A very effective access to polysubstituted α-diazocarbonyl compounds

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TBAB-catalyzed 1,6-conjugate diazotization of para-quinone methides: A very effective access to polysubstituted α-diazocarbonyl compounds

A highly efficient diazotization of diazoacetates with para-quinone methides has been established via a tetrabutyl ammonium bromide (TBAB)-catalyzed 1,6-conjugated addition pathway. This methodology affords a convenient, safe, and rapid way to generating diverse polysubstituted α-diazocarbonyl compounds, displaying good functional group tolerance, high atom economy, and easy accessibility.

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来源期刊

Journal of Saudi Chemical Society CHEMISTRY, MULTIDISCIPLINARY-

CiteScore

8.90

自引率

1.80%

发文量

120

审稿时长

38 days

期刊介绍： Journal of Saudi Chemical Society is an English language, peer-reviewed scholarly publication in the area of chemistry. Journal of Saudi Chemical Society publishes original papers, reviews and short reports on, but not limited to: •Inorganic chemistry •Physical chemistry •Organic chemistry •Analytical chemistry Journal of Saudi Chemical Society is the official publication of the Saudi Chemical Society and is published by King Saud University in collaboration with Elsevier and is edited by an international group of eminent researchers.