B Dembélé, B Doumbia, F Diawara, M M Koureichi, M Telly, A Traoré, Y I Coulibaly
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引用次数: 0
摘要
导言一些学者认为ABO血型（ABOS）与感染SARS CoV-2的风险有关。本研究旨在确定马里国家公共卫生研究所（INSP）的 ABOS 血型对 COVID-19 的易感性：这是一项非配对病例对照研究。病例（402例）为COVID-19患者，对照组（5438例）为穆斯林朝圣者，他们都在马里国家公共卫生研究所进行过ABO血型检测。使用 SPSS version25 软件进行了逻辑回归，以确定与 SARS-CoV-2 感染状况相关的因素：血型的频率如下病例的血型为 O(34%)、B(30%)、A(28%)、AB(8%)；对照组的血型为 O(42%)、B(27%)、A(25%)、AB(6%)。COVID-19 阳性与血型 A（OR=1.17；CI95%[0.93-1.47]）、B（OR=1.11；CI95%[0.89-1.39]）和 AB（OR=1.41；CI95%[0.97-2.06]）无显著相关性。然而，O 型血受试者患 COVID-19 的几率是非 O 型血的 28 倍（OR=0.72；CI95%[0.58-0.89]）：结论：研究结果表明，血型为O型的人感染SARS CoV-2的几率比非O型的人低。这不应影响在 ABOS 群体中使用屏障措施。
[Susceptibility Of ABOS Blood Groups To COVID-19 At The National Institute Of Public Health (INSP) Of Mali In 2020].
Introduction: Several authors have suggested an association between the ABO system (ABOS) and the risk of SARS CoV-2 infection. The objective of the present study was to identify the susceptibility of ABOS blood groups to COVID-19 at the National Institute of Public Health (INSP) of Mali.
Material and methods: This was an unpaired case-control study. The cases (402) were COVID-19 patients, and the controls (5438) were Muslim pilgrims, all of whom had undergone ABO blood grouping at the INSP. Logistic regression was performed to identify factors associated with SARS-CoV-2 infection status using SPSS version25 software.
Results: Blood types had the following frequencies: O(34%), B(30%), A(28%), AB(8%) for cases and O(42%), B(27%), A(25%), AB(6%) for controls. COVID-19 positive status was not significantly associated with blood groups A(oR=1.17; CI95%[0.93-1.47]), B(OR=1.11; CI95%[0.89-1.39]) and AB(OR=1.41; CI95%[0.97-2.06]). However, blood group O subjects were 28 times less likely to have COVID-19 than non-O(OR=0.72; CI95%[0.58-0.89).
Conclusion: The results show that blood group O individuals were less likely to have SARS CoV-2 infection than non-O individuals. This should not affect the use of barrier measures in ABOS groups.
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