凝胶浸泡内镜黏膜切除术治疗早期胃肿瘤:一项多中心病例系列研究。

IF 2.2 Q3 GASTROENTEROLOGY & HEPATOLOGY
Endoscopy International Open Pub Date : 2024-03-18 eCollection Date: 2024-03-01 DOI:10.1055/a-2271-2411
Hidenori Kimura, Yoichi Yamamoto, Yohei Yabuuchi, Kohei Shigeta, Masao Yoshida, Soichiro Nagao, Akito Noguchi, Yukihiro Morita, Shuhei Shintani, Osamu Inatomi, Hiroyuki Ono, Akira Andoh
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引用次数: 0

摘要

已有多个病例报告表明,凝胶浸泡内镜粘膜切除术(GI-EMR)对胃肿瘤有疗效。然而,还没有研究对胃癌 GI-EMR 的治疗效果进行评估。本研究旨在探讨胃肠道黏膜切除术治疗早期胃肿瘤的有效性和安全性。9名患者(17个病灶)接受了胃肠道造影术,病灶中位尺寸为10毫米(四分位距[IQR]5-13毫米)。所有病灶均突出或平坦隆起。手术时间中位数为 3 分钟(IQR 2-5),所有病例均实现了全切。在15个肿瘤病灶中,R0切除率为86.7%(13/15个病灶)。不良事件包括两例需要止血的即刻出血,均在内镜下得到控制。无延迟出血或穿孔发生。总之,胃肠道造影术可能是治疗早期小型胃肿瘤的一种安全有效的方法。然而,由于本研究的样本较少,还需要进一步研究这项技术的适应症。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Gel immersion endoscopic mucosal resection for early gastric neoplasms: a multicenter case series study.

Several cases have been reported that suggest the efficacy of gel immersion endoscopic mucosal resection (GI-EMR) for gastric neoplasms. However, no study has evaluated treatment outcomes of GI-EMR for gastric neoplasms. This study aimed to investigate the efficacy and safety of GI-EMR for early gastric neoplasms. Nine patients (17 lesions) undergoing gastric GI-EMR were included, with a median lesion size of 10 mm (interquartile range [IQR] 5-13 mm). All lesions were protruding or flat elevated. The median procedure time was 3 minutes (IQR 2-5) and en bloc resection was achieved in all cases. Among 15 neoplastic lesions, the R0 resection rate was 86.7% (13/15 lesions). Adverse events included immediate bleeding requiring hemostasis in two cases, which was controlled endoscopically. No delayed bleeding or perforation occurred. In conclusion, GI-EMR may be a safe and effective treatment for early, small gastric neoplasms. However, due to the small sample in the present study, further investigation is required regarding the indication for this technique.

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来源期刊
Endoscopy International Open
Endoscopy International Open GASTROENTEROLOGY & HEPATOLOGY-
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3.80%
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