DiGAlign：用于比较基因组学的多功能交互式可视化序列比对。

IF 2.1 4区环境科学与生态学 Q3 BIOTECHNOLOGY & APPLIED MICROBIOLOGY

Microbes and Environments Pub Date : 2024-01-01 DOI:10.1264/jsme2.ME23061

Yosuke Nishimura, Kohei Yamada, Yusuke Okazaki, Hiroyuki Ogata

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引用次数: 0

摘要

随着可用基因组信息的激增，比较基因组学已成为了解微生物生态学和进化的核心方法。我们开发了 DiGAlign (https://www.genome.jp/digalign/)，它是一个网络服务器，以直观的界面为比较基因组学提供多种功能。用户只需上传感兴趣的核苷酸序列（从特定区域到微生物和病毒的整个基因组图谱），就能对同源图谱进行高度可定制的可视化处理。DiGAlign 将为广大生物研究人员，尤其是实验生物学家提供服务，它具有多方面的功能，可以快速鉴定感兴趣的基因组序列并生成可供发表的图谱。

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DiGAlign: Versatile and Interactive Visualization of Sequence Alignment for Comparative Genomics.

With the explosion of available genomic information, comparative genomics has become a central approach to understanding microbial ecology and evolution. We developed DiGAlign (https://www.genome.jp/digalign/), a web server that provides versatile functionality for comparative genomics with an intuitive interface. It allows the user to perform the highly customizable visualization of a synteny map by simply uploading nucleotide sequences of interest, ranging from a specific region to the whole genome landscape of microorganisms and viruses. DiGAlign will serve a wide range of biological researchers, particularly experimental biologists, with multifaceted features that allow the rapid characterization of genomic sequences of interest and the generation of a publication-ready figure.

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来源期刊

Microbes and Environments 生物-生物工程与应用微生物

CiteScore

4.10

自引率

13.60%

发文量

审稿时长

3 months

期刊介绍： Microbial ecology in natural and engineered environments; Microbial degradation of xenobiotic compounds; Microbial processes in biogeochemical cycles; Microbial interactions and signaling with animals and plants; Interactions among microorganisms; Microorganisms related to public health; Phylogenetic and functional diversity of microbial communities; Genomics, metagenomics, and bioinformatics for microbiology; Application of microorganisms to agriculture, fishery, and industry; Molecular biology and biochemistry related to environmental microbiology; Methodology in general and environmental microbiology; Interdisciplinary research areas for microbial ecology (e.g., Astrobiology, and Origins of Life); Taxonomic description of novel microorganisms with ecological perspective; Physiology and metabolisms of microorganisms; Evolution of genes and microorganisms; Genome report of microorganisms with ecological perspective.