急性失代偿性心力衰竭住院患者肝硬变的预后价值：一项荟萃分析。

IF 1.3 Q3 RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING

Journal of Ultrasound Pub Date : 2024-09-01 Epub Date: 2024-03-18 DOI:10.1007/s40477-024-00873-0

Noemi Macerola, Laura Riccardi, Enrico Di Stasio, Massimo Montalto, Antonio Gasbarrini, Maurizio Pompili, Matteo Garcovich

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引用次数: 0

摘要

目的：心力衰竭（HF）是影响全球数百万人的主要健康问题。近年来，人们一直在努力确定这些患者预后不良的预测因素。本系统综述和荟萃分析的目的是揭示剪切波弹性成像技术评估的肝脏僵硬度（LS）与心力衰竭之间的相关性，尤其关注 LS 对心血管预后的预测价值：我们检索了 PUBMED 数据库（截至 2023 年 5 月 1 日）中有关急性失代偿性心力衰竭（ADHF）住院患者 LS 与心血管预后相关性的研究。我们进行了一项荟萃分析，以估计 LS 在预测 ADHF 患者预后方面的疗效：我们分析了 7 项研究（共 677 例患者）的数据，这些研究评估了 LS 在预测 ADHF 住院患者心血管预后方面的预后价值。汇总分析表明，肝脏僵硬度升高与不良心脏事件风险升高有关（危险比 1.07 [1.03, 1.12]，95% CI）：结论：肝僵硬度增加与心房颤动住院患者的不良预后有关，可能有助于有效识别预后较差的高风险患者。

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Prognostic value of liver stiffness in patients hospitalized for acute decompensated heart failure: a meta-analysis.

Purpose: Heart failure (HF) is a major health problem affecting millions of people worldwide. In the latest years, many efforts have been made to identify predictors of poor prognosis in these patients. The aim of this systematic review and meta-analysis was to enlighten the correlation between liver stiffness (LS), assessed by Shear Wave Elastography techniques, and HF, particularly focusing on the prognostic value of LS on cardiovascular outcomes.

Methods: We searched the PUBMED databases (up to May 1st, 2023) for studies that enlightened the correlation between LS and cardiovascular outcomes in patients hospitalized for acute decompensated heart failure (ADHF). We performed a meta-analysis to estimate the efficacy of LS in predicting the prognosis of patients with ADHF.

Results: We analyzed data from 7 studies, comprising 677 patients, that assessed the prognostic value of LS in predicting cardiovascular outcomes in patients hospitalized for ADHF. The pooled analysis showed that increased liver stiffness was associated with higher risk of adverse cardiac events (hazard ratio 1.07 [1.03, 1.12], 95% CI).

Conclusion: Increased LS is associated with poor prognosis in patients hospitalized for HF and might help effectively identify those patients at high risk for worse outcomes.

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来源期刊

Journal of Ultrasound RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING-

CiteScore

4.10

自引率

15.00%

发文量

133

期刊介绍： The Journal of Ultrasound is the official journal of the Italian Society for Ultrasound in Medicine and Biology (SIUMB). The journal publishes original contributions (research and review articles, case reports, technical reports and letters to the editor) on significant advances in clinical diagnostic, interventional and therapeutic applications, clinical techniques, the physics, engineering and technology of ultrasound in medicine and biology, and in cross-sectional diagnostic imaging. The official language of Journal of Ultrasound is English.