检测和分析急性荨麻疹患者的常用感染指标。

IF 2.5 4区 医学 Q3 ALLERGY
International Archives of Allergy and Immunology Pub Date : 2024-01-01 Epub Date: 2024-03-18 DOI:10.1159/000536642
Jia Deng, Jifeng Liu, Wenzhong Xiang
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引用次数: 0

摘要

简介本研究探讨了急性荨麻疹患者外周血白细胞、中性粒细胞、C反应蛋白(CRP)和降钙素原(PCT)的相关性和临床意义:方法:对急性荨麻疹患者进行全血细胞计数(含差值)、CRP 和 PCT 检测。共将 614 名急性荨麻疹患者分为三组:第一组为白细胞和中性粒细胞计数升高的患者,第二组为白细胞和中性粒细胞计数正常的患者,第三组为白细胞和中性粒细胞计数异常的患者。对三组患者的白细胞、中性粒细胞、CRP和PCT水平进行了相关分析:Kruskal-Wallis非参数检验结果显示,三组患者的白细胞、中性粒细胞、CRP和PCT差异有统计学意义(P< 0.001)。然而,第二组和第三组之间的 CRP 和 PCT 无统计学差异(p < 0.001、p = 0.0041、p = 0.0032)。斯皮尔曼相关分析中的其他多重比较表明,两组之间存在统计学意义上的显著差异(p = 0.55)。在所有组别中,CRP-PCT 与白细胞-中性粒细胞之间的相关性差异有统计学意义(p = 0.53):白细胞和中性粒细胞对药物和压力对身体的影响非常敏感。结合 CRP 和 PCT 以及血常规检查,可全面评估患者感染的存在和严重程度,为抗生素治疗提供指导。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Detection and Analysis of Commonly Used Infection Indicators in Patients with Acute Urticaria.

Introduction: In this study, we investigated the correlation and clinical significance of peripheral blood leukocytes, neutrophils, C-reactive protein (CRP), and procalcitonin (PCT) in patients with acute urticaria.

Methods: Complete blood count with differential, CRP, and PCT tests were conducted on patients with acute urticaria. A total of 614 patients with acute urticaria were divided into three groups: the first group consisted of patients with elevated leukocyte and neutrophil count, the second group consisted of patients with normal leukocyte and neutrophil count, and the third group consisted of patients with abnormal leukocyte and neutrophil count. A correlation analysis was conducted to investigate the levels of leukocytes, neutrophils, CRP, and PCT in the three groups.

Results: The results of Kruskal-Wallis' nonparametric test revealed statistically significant variations in leukocytes, neutrophils, CRP, and PCT among the three groups (p < 0.001). However, CRP and PCT showed no statistically significant differences between the second and third groups (p < 0.001, p = 0.0041, p = 0.0032). Additional multiple comparisons in Spearman correlation analysis indicated statistically significant differences (p = 0.55). Across all groups, there was a statistically significant difference in the correlation between CRP-PCT and leukocytes-neutrophils (p = 0.53).

Conclusion: Leukocytes and neutrophils are sensitive to the impact of medications and stress on the body. Combining CRP and PCT, as well as routine blood test, may be a comprehensive assessment of infection presence and severity in patients, providing guidance for antibiotic treatment.

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来源期刊
CiteScore
5.60
自引率
3.60%
发文量
105
审稿时长
2 months
期刊介绍: ''International Archives of Allergy and Immunology'' provides a forum for basic and clinical research in modern molecular and cellular allergology and immunology. Appearing monthly, the journal publishes original work in the fields of allergy, immunopathology, immunogenetics, immunopharmacology, immunoendocrinology, tumor immunology, mucosal immunity, transplantation and immunology of infectious and connective tissue diseases.
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