Brincidofovir 用于治疗因怀疑对替考韦瑞产生抗药性而导致病情恶化的晚期艾滋病病毒感染者。

IF 1.4 4区医学 Q4 IMMUNOLOGY

International Journal of STD & AIDS Pub Date : 2024-07-01 Epub Date: 2024-03-19 DOI:10.1177/09564624241238813

Iris Harrison, Kathryn DeSear, Barbara A Santevecchi, Veena Venugopalan, Kartikeya Cherabuddi, Nicole Iovine, Nila Radhakrishnan

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引用次数: 0

摘要

一名晚期艾滋病毒感染者在初次感染水痘 2-3 个月后出现疣状斑块。他接受了两个疗程的替考韦瑞（tecovirimat）治疗，但最初的痘痕并未消退，反而出现了新的痘痕，这引起了他对耐药性的担忧。他接受了两个剂量的布林昔多福韦治疗，6 个月后病情有所好转。

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Brincidofovir for disease progression due to suspected tecovirimat resistance in association with advanced HIV.

A man with advanced HIV presented with verrucous plaques 2-3 months after initial mpox infection. He received two courses of tecovirimat without resolution of initial mpox lesions and development of new lesions raising concern for resistance. He was treated with two doses of brincidofovir and demonstrated improvement 6 months later.

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来源期刊

International Journal of STD & AIDS 医学-传染病学

CiteScore

2.60

自引率

7.10%

发文量

144

审稿时长

3-6 weeks

期刊介绍： The International Journal of STD & AIDS provides a clinically oriented forum for investigating and treating sexually transmissible infections, HIV and AIDS. Publishing original research and practical papers, the journal contains in-depth review articles, short papers, case reports, audit reports, CPD papers and a lively correspondence column. This journal is a member of the Committee on Publication Ethics (COPE).