游离颊脂肪垫移植用于药物性颌骨坏死的骨缺损填充:新颖的手术方法

IF 3.4 3区 医学 Q1 DENTISTRY, ORAL SURGERY & MEDICINE
Jen-Wei Cheng , Kai-Yuan Hsiao , Meng-Yen Chen , Tze-Ta Huang , Ken-chung Chen
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引用次数: 0

摘要

与药物相关的颌骨骨坏死(MRONJ)目前主要采用手术治疗,其治愈率高于保守治疗。然而,由于药物作用造成的血管不畅,螯合切除术后骨缺损的处理仍是一个具有挑战性的问题。使用带蒂颊脂垫(PBFP)填充骨缺损已成为常见且有效的方法,但仅限于上颌后部。为了增加颊脂肪垫的优势,我们探索了一种新的治疗方法,即使用游离颊脂肪垫(FBFP)来填充上颌后部以外的骨缺损。虽然游离颊脂垫已被用于口腔缺损重建,但目前发表的病例都是在血液供应良好的受体部位使用。在血管供应较差的缺损(如 MRONJ)中还没有使用过。本文介绍了使用 FBFP 填充 8 名被诊断为 MRONJ 的患者的手术缺损,这些患者都接受了序列切除术和碟状切除术。在随访期间,伤口愈合良好,无明显组织凹陷。根据成功的治疗经验,FBFP 是一种可靠的治疗方法,可用于治疗通过外科手术治疗的血管缺损(如 MRONJ)。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Free buccal fat pad graft for the bone defect filling of medication-related osteonecrosis of the jaws: A novel surgical approach

Surgical intervention for medication-related jaw osteonecrosis (MRONJ) is currently the main treatment method, offering a higher healing rate than conservative approaches. However, the management of bony defects after sequestrectomy remains a challenging issue due to poor vascularization from the drug effect. The use of pedicled buccal fat pad (PBFP) for filling bone defects has become common and effective but is limited to the posterior maxillary region. To add to the advantages of the buccal fat pad, we explored a novel treatment approach using a free buccal fat pad (FBFP) to fill bone defects other than the posterior maxilla. While the FBFP has been employed in oral defect reconstruction, currently published cases have been utilized in recipient sites with good blood supply. There has yet to be any usage in poor vascularization defects like MRONJ. This article describes that the FBFP was used to fill the surgical defects of 8 patients who were diagnosed with MRONJ and who underwent sequestrectomy and saucerization. During follow-up visits, there was excellent wound healing and no significant tissue depression. Based on successful treatment experiences, FBFP is a reliable therapeutic option for the management of poor vascularization defects like MRONJ treated through surgical intervention.

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来源期刊
Journal of Dental Sciences
Journal of Dental Sciences 医学-牙科与口腔外科
CiteScore
5.10
自引率
14.30%
发文量
348
审稿时长
6 days
期刊介绍: he Journal of Dental Sciences (JDS), published quarterly, is the official and open access publication of the Association for Dental Sciences of the Republic of China (ADS-ROC). The precedent journal of the JDS is the Chinese Dental Journal (CDJ) which had already been covered by MEDLINE in 1988. As the CDJ continued to prove its importance in the region, the ADS-ROC decided to move to the international community by publishing an English journal. Hence, the birth of the JDS in 2006. The JDS is indexed in the SCI Expanded since 2008. It is also indexed in Scopus, and EMCare, ScienceDirect, SIIC Data Bases. The topics covered by the JDS include all fields of basic and clinical dentistry. Some manuscripts focusing on the study of certain endemic diseases such as dental caries and periodontal diseases in particular regions of any country as well as oral pre-cancers, oral cancers, and oral submucous fibrosis related to betel nut chewing habit are also considered for publication. Besides, the JDS also publishes articles about the efficacy of a new treatment modality on oral verrucous hyperplasia or early oral squamous cell carcinoma.
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