{"title":"Bawang Dayak Eleutherine bulbosa (Mill.) Urb.抗痘霜","authors":"Susi Novaryatiin, Rikha Nuramanah, Isnawati Isnawati, Selvia Susanti, Drenikha Sikhe Ryba Kanahuang, Syahrida Dian Ardhany","doi":"10.1016/j.hermed.2024.100869","DOIUrl":null,"url":null,"abstract":"<div><h3>Introduction</h3><p>Several studies have reported the ability of Bawang Dayak cream to inhibit <em>Cutibacterium acnes</em>, but the lack of specific formulations has led to its ineffectiveness. This is indicated by a smaller inhibition zone and the predominant scent of the plant. Therefore, this study aims to assess the physical characteristics and antibacterial activity of two modified formulations of Bawang Dayak anti-acne cream.</p></div><div><h3>Methods</h3><p>Two modified formulations of Bawang Dayak anti-acne cream were prepared, namely M1 (containing peppermint water) and M2 (comprising peppermint water, cinnamon extract, and honey). Each formulation had four concentrations: 5% (F1), 10% (F2), 15% (F3), and 20% (F4). The physical characteristics were then examined. The antibacterial activity test was carried out using the disc-diffusion method against acne-causing bacteria.</p></div><div><h3>Results</h3><p>The addition of peppermint water to the cream formula masked the odour of Bawang Dayak. All the formulas examined met the requirements of the homogeneity, pH, and spreadability tests. However, the adhesion test showed that only F2 and F4 of M2 met the requirement. The results also showed that M1 had better antibacterial activity compared to M2.</p></div><div><h3>Conclusions</h3><p>This study found that all the formulas observed passed the homogeneity, pH, and spreadability tests. Only F2 and F4 of M2 met the requirements of the adhesion tests. M1 exhibited superior antibacterial activity compared to the M2. F1 of M1 showed the highest antibacterial activity against <em>Staphylococcus epidermidis.</em> Further investigation was needed to evaluate the effectiveness of M2 against <em>S. epidermidis</em> and <em>Staphylococcus aureus</em>, as well as assess the stability.</p></div>","PeriodicalId":56077,"journal":{"name":"Journal of Herbal Medicine","volume":"45 ","pages":"Article 100869"},"PeriodicalIF":2.2000,"publicationDate":"2024-03-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Formulation, physical characterization, and antibacterial activity of modifications of Bawang Dayak Eleutherine bulbosa (Mill.) Urb. anti-acne cream\",\"authors\":\"Susi Novaryatiin, Rikha Nuramanah, Isnawati Isnawati, Selvia Susanti, Drenikha Sikhe Ryba Kanahuang, Syahrida Dian Ardhany\",\"doi\":\"10.1016/j.hermed.2024.100869\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<div><h3>Introduction</h3><p>Several studies have reported the ability of Bawang Dayak cream to inhibit <em>Cutibacterium acnes</em>, but the lack of specific formulations has led to its ineffectiveness. This is indicated by a smaller inhibition zone and the predominant scent of the plant. Therefore, this study aims to assess the physical characteristics and antibacterial activity of two modified formulations of Bawang Dayak anti-acne cream.</p></div><div><h3>Methods</h3><p>Two modified formulations of Bawang Dayak anti-acne cream were prepared, namely M1 (containing peppermint water) and M2 (comprising peppermint water, cinnamon extract, and honey). Each formulation had four concentrations: 5% (F1), 10% (F2), 15% (F3), and 20% (F4). The physical characteristics were then examined. The antibacterial activity test was carried out using the disc-diffusion method against acne-causing bacteria.</p></div><div><h3>Results</h3><p>The addition of peppermint water to the cream formula masked the odour of Bawang Dayak. All the formulas examined met the requirements of the homogeneity, pH, and spreadability tests. However, the adhesion test showed that only F2 and F4 of M2 met the requirement. The results also showed that M1 had better antibacterial activity compared to M2.</p></div><div><h3>Conclusions</h3><p>This study found that all the formulas observed passed the homogeneity, pH, and spreadability tests. Only F2 and F4 of M2 met the requirements of the adhesion tests. M1 exhibited superior antibacterial activity compared to the M2. F1 of M1 showed the highest antibacterial activity against <em>Staphylococcus epidermidis.</em> Further investigation was needed to evaluate the effectiveness of M2 against <em>S. epidermidis</em> and <em>Staphylococcus aureus</em>, as well as assess the stability.</p></div>\",\"PeriodicalId\":56077,\"journal\":{\"name\":\"Journal of Herbal Medicine\",\"volume\":\"45 \",\"pages\":\"Article 100869\"},\"PeriodicalIF\":2.2000,\"publicationDate\":\"2024-03-15\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Journal of Herbal Medicine\",\"FirstCategoryId\":\"3\",\"ListUrlMain\":\"https://www.sciencedirect.com/science/article/pii/S2210803324000265\",\"RegionNum\":4,\"RegionCategory\":\"医学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q2\",\"JCRName\":\"INTEGRATIVE & COMPLEMENTARY MEDICINE\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Journal of Herbal Medicine","FirstCategoryId":"3","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S2210803324000265","RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q2","JCRName":"INTEGRATIVE & COMPLEMENTARY MEDICINE","Score":null,"Total":0}
Formulation, physical characterization, and antibacterial activity of modifications of Bawang Dayak Eleutherine bulbosa (Mill.) Urb. anti-acne cream
Introduction
Several studies have reported the ability of Bawang Dayak cream to inhibit Cutibacterium acnes, but the lack of specific formulations has led to its ineffectiveness. This is indicated by a smaller inhibition zone and the predominant scent of the plant. Therefore, this study aims to assess the physical characteristics and antibacterial activity of two modified formulations of Bawang Dayak anti-acne cream.
Methods
Two modified formulations of Bawang Dayak anti-acne cream were prepared, namely M1 (containing peppermint water) and M2 (comprising peppermint water, cinnamon extract, and honey). Each formulation had four concentrations: 5% (F1), 10% (F2), 15% (F3), and 20% (F4). The physical characteristics were then examined. The antibacterial activity test was carried out using the disc-diffusion method against acne-causing bacteria.
Results
The addition of peppermint water to the cream formula masked the odour of Bawang Dayak. All the formulas examined met the requirements of the homogeneity, pH, and spreadability tests. However, the adhesion test showed that only F2 and F4 of M2 met the requirement. The results also showed that M1 had better antibacterial activity compared to M2.
Conclusions
This study found that all the formulas observed passed the homogeneity, pH, and spreadability tests. Only F2 and F4 of M2 met the requirements of the adhesion tests. M1 exhibited superior antibacterial activity compared to the M2. F1 of M1 showed the highest antibacterial activity against Staphylococcus epidermidis. Further investigation was needed to evaluate the effectiveness of M2 against S. epidermidis and Staphylococcus aureus, as well as assess the stability.
期刊介绍:
The Journal of Herbal Medicine, the official journal of the National Institute of Medical Herbalists, is a peer reviewed journal which aims to serve its readers as an authoritative resource on the profession and practice of herbal medicine. The content areas of the journal reflect the interests of Medical Herbalists and other health professionals interested in the clinical and professional application of botanical medicines. The objective is to strengthen the research and educational base of herbal medicine with research papers in the form of case studies, original research articles and reviews, monographs, clinical trials and relevant in vitro studies. It also publishes policy statements, opinion pieces, book reviews, conference proceedings and profession related information such as pharmacovigilance reports providing an information source for not only the Herbal Practitioner but any Health professional with an interest in phytotherapy.