意大利巴勒莫大学医院疫苗接种中心联合接种 COVID-19 和季节性流感疫苗的实际经验。

IF 4.1 4区 医学 Q2 BIOTECHNOLOGY & APPLIED MICROBIOLOGY
Human Vaccines & Immunotherapeutics Pub Date : 2024-12-31 Epub Date: 2024-03-18 DOI:10.1080/21645515.2024.2327229
Claudio Costantino, Walter Mazzucco, Arianna Conforto, Livia Cimino, Alessia Pieri, Sara Rusignolo, Nicole Bonaccorso, Floriana Bravatà, Laura Pipitone, Martina Sciortino, Marcello Tocco, Elena Zarcone, Giorgio Graziano, Fabio Tramuto, Carmelo Massimo Maida, Alessandra Casuccio, Francesco Vitale
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引用次数: 0

摘要

随着流感大流行,全球流感病毒流通量减少,世卫组织报告,在 2021/22 季度,流感实验室检测阳性率低于 3%。流感监测系统预计,2022/2023 季度北半球将出现流感病例高峰,意大利卫生部建议在 2022/2023 季度常规联合接种 COVID-19 二价流感疫苗。在巴勒莫大学医院(UH)的疫苗接种中心,超过700名受试者在2021/2022年接种季节接受了流感和COVID-19强化剂联合接种。2022年10月至12月,巴勒莫大学医院疫苗接种中心开展了一项横断面研究,分析了与坚持联合接种流感疫苗和COVID-19季节性疫苗相关的态度和因素。在1,263名受访者中,74.7%(n = 944)接受了季节性流感和COVID-19疫苗联合接种。据报告,接受联合接种的主要原因是对卫生部建议的信心(41.3%)。在多变量分析中,年龄≤ 59 岁(AdjOR:2.48;CIs95%:1.89-3.65)、男性(AdjOR:1.51;CIs95%:1.27-1.75)、医疗保健专业人员(HCPs)(AdjOR:1.66;CIs95%:1.08-2.57)和在 2021/2022 年期间接受过联合用药者(AdjOR:41.6;CIs95%:25.5-67.9)在 2022/23 年期间接受联合用药的可能性显著增加。从获得的数据来看,HCPs 在接受并随后促进 COVID-19 和流感疫苗联合接种方面的作用至关重要,而在上一季节接受联合接种则是下一季节接受联合接种的主要动力,这支持了这一程序的安全性和有效性。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Real-life experience on COVID-19 and seasonal influenza vaccines co-administration in the vaccination hub of the University Hospital of Palermo, Italy.

With the pandemic, there has been a global reduction in influenza virus circulation, with WHO reporting, during 2021/22 season, laboratory testing positivity rate for influenza of less than 3%. Influenza surveillance systems anticipated a peak of influenza cases in the Northern Hemisphere during 2022/2023 season and the Italian Ministry of Health recommended the routinary co-administration of influenza with bivalent COVID-19 vaccines for the 2022/2023 season. At the Vaccination Hub of the University Hospital (UH) of Palermo, more than 700 subjects received influenza and COVID-19 booster doses in co-administration, during the 2021/2022 season. A cross-sectional study analyzing attitudes and factors associated with adherence to influenza and COVID-19 seasonal vaccines co-administration was conducted at the Vaccination Hub of the UH of Palermo, from October to December 2022. Among the 1,263 respondents, 74.7% (n = 944) received the co-administration of seasonal influenza and COVID-19 vaccines. The main reason reported for accepting it was confidence in the recommendations of the Health Ministry (41.3%). At the multivariable analysis, subjects aged ≤ 59 y old (AdjOR: 2.48; CIs95%: 1.89-3.65), male (AdjOR: 1.51; CIs95%: 1.27-1.75), Health-care professionals (HCPs) (AdjOR: 1.66; CIs95%: 1.08-2.57) and those who received co-administration during 2021/2022 (AdjOR: 41.6; CIs95%: 25.5-67.9) were significantly more prone to receive co-administration during 2022/23 season. From data obtained, the role of HCPs in accepting and then promoting co-administration of COVID-19 and influenza vaccines is crucial, as well as receiving co-administration in the previous season that represented the main drive for accepting it in the following seasons, supporting safety and effectiveness of this procedure.

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来源期刊
Human Vaccines & Immunotherapeutics
Human Vaccines & Immunotherapeutics BIOTECHNOLOGY & APPLIED MICROBIOLOGY-IMMUNOLOGY
CiteScore
7.90
自引率
8.30%
发文量
489
审稿时长
3-6 weeks
期刊介绍: (formerly Human Vaccines; issn 1554-8619) Vaccine research and development is extending its reach beyond the prevention of bacterial or viral diseases. There are experimental vaccines for immunotherapeutic purposes and for applications outside of infectious diseases, in diverse fields such as cancer, autoimmunity, allergy, Alzheimer’s and addiction. Many of these vaccines and immunotherapeutics should become available in the next two decades, with consequent benefit for human health. Continued advancement in this field will benefit from a forum that can (A) help to promote interest by keeping investigators updated, and (B) enable an exchange of ideas regarding the latest progress in the many topics pertaining to vaccines and immunotherapeutics. Human Vaccines & Immunotherapeutics provides such a forum. It is published monthly in a format that is accessible to a wide international audience in the academic, industrial and public sectors.
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