性别对多动症认知控制的影响:女孩抑制迟缓,男孩抑制较少,且都表现出较高的反应变异性。

IF 2.7 3区 医学 Q2 PSYCHIATRY
Journal of Attention Disorders Pub Date : 2024-07-01 Epub Date: 2024-03-16 DOI:10.1177/10870547241237242
Beatrice Ojuri, Alyssa DeRonda, Micah Plotkin, Stewart H Mostofsky, Keri S Rosch
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引用次数: 0

摘要

目的确定患有多动症的女孩和男孩在多项任务(走/不走、停止信号和侧翼)和表现指标(反应速度、变异性和错误)中的认知控制部分是否表现出明显的缺陷:共有 300 名 8 至 12 岁患有多动症(n = 210,58 名女孩)或发育正常(TD;n = 99,37 名女孩)的儿童完成了所有任务。对传统的反应测量(如反应时间的平均值和标准偏差、抑制误差和停止信号反应时间)和反应时间的前高斯模型(mu、sigma和tau)进行了分析:结果:在反应速度较慢的情况下,女孩表现出了完整的反应抑制,而男孩则出现了更多的抑制错误,反应速度也没有减慢。与 TD 儿童相比,患有多动症的女孩和男孩都表现出更高的反应变异性和更差的干扰控制能力:结论:患有多动症的女孩和男孩在认知控制方面表现出明显的缺陷,这对于了解多动症的病理生理学可能非常重要。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
The Impact of Sex on Cognitive Control in ADHD: Girls Slow to Inhibit, Boys Inhibit Less, and Both Show Higher Response Variability.

Objective: To determine whether girls and boys with ADHD show distinct impairments in components of cognitive control across multiple tasks (go/no-go, stop signal, and flanker) and performance metrics (response speed, variability, and errors).

Method: A total of 300 children, ages 8 to 12 years with ADHD (n = 210, 58 girls) or typically developing (TD; n = 99, 37 girls), completed all tasks. Traditional response measures (e.g., mean and standard deviation of reaction time, inhibition errors, and stop signal reaction time) and ex-Gaussian modeling of reaction times (mu, sigma, and tau) were analyzed.

Results: Girls showed intact response inhibition in the context of slower response speed, while boys made more inhibition errors and did not slow their response speed. Both girls and boys with ADHD showed higher response variability and poorer interference control than TD children.

Conclusion: Girls and boys with ADHD show distinct impairments in cognitive control that may be important for understanding the pathophysiology of ADHD.

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来源期刊
CiteScore
7.60
自引率
6.70%
发文量
71
审稿时长
6-12 weeks
期刊介绍: Journal of Attention Disorders (JAD) focuses on basic and applied science concerning attention and related functions in children, adolescents, and adults. JAD publishes articles on diagnosis, comorbidity, neuropsychological functioning, psychopharmacology, and psychosocial issues. The journal also addresses practice, policy, and theory, as well as review articles, commentaries, in-depth analyses, empirical research articles, and case presentations or program evaluations.
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