利用脱细胞磁性微型机器人为软骨再生输送功能细胞(小号 11/2024)

IF 12.1 2区 材料科学 Q1 CHEMISTRY, MULTIDISCIPLINARY
Small Pub Date : 2024-03-15 DOI:10.1002/smll.202470091
Hanjin Huang, Junyang Li, Cheng Wang, Liuxi Xing, Hui Cao, Chang Wang, Chung Yan Leung, Zongze Li, Yue Xi, Hua Tian, Feng Li, Dong Sun
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引用次数: 0

摘要

软骨再生在文章编号 2304088 中,李锋、孙东及其合作者通过脱细胞和磁化相结合的方案开发了细胞输送微型机器人。它源自脱细胞的天然猪软骨细胞外基质,其生物力学环境与人体软骨相似,能有效负载功能细胞,同时保持高流动性。在临床前试验中,作者证明了它对软骨再生的治疗效果。
本文章由计算机程序翻译,如有差异,请以英文原文为准。

Using Decellularized Magnetic Microrobots to Deliver Functional Cells for Cartilage Regeneration (Small 11/2024)

Using Decellularized Magnetic Microrobots to Deliver Functional Cells for Cartilage Regeneration (Small 11/2024)

Using Decellularized Magnetic Microrobots to Deliver Functional Cells for Cartilage Regeneration (Small 11/2024)

Cartilage Regeneration

In article number 2304088, Feng Li, Dong Sun, and co-workers developed the cell delivery microrobot by a protocol combining decellularization and magnetization. It is derived from the decellularized natural porcine cartilage extracellular matrix, which has a biomechanical environment to that of human cartilage and can efficiently load functional cells while maintaining high mobility. In preclinical tests, the authors demonstrate the therapeutical effects of it for cartilage regeneration.

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来源期刊
Small
Small 工程技术-材料科学:综合
CiteScore
17.70
自引率
3.80%
发文量
1830
审稿时长
2.1 months
期刊介绍: Small serves as an exceptional platform for both experimental and theoretical studies in fundamental and applied interdisciplinary research at the nano- and microscale. The journal offers a compelling mix of peer-reviewed Research Articles, Reviews, Perspectives, and Comments. With a remarkable 2022 Journal Impact Factor of 13.3 (Journal Citation Reports from Clarivate Analytics, 2023), Small remains among the top multidisciplinary journals, covering a wide range of topics at the interface of materials science, chemistry, physics, engineering, medicine, and biology. Small's readership includes biochemists, biologists, biomedical scientists, chemists, engineers, information technologists, materials scientists, physicists, and theoreticians alike.
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