验证运动期间缺氧暴露的空气存储系统。

IF 1.6 4区 医学 Q4 BIOPHYSICS
High altitude medicine & biology Pub Date : 2024-06-01 Epub Date: 2024-03-15 DOI:10.1089/ham.2023.0122
Matheus S Norberto, João Victor G Torini, Matheus S Firmino, Marcelo Papoti
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引用次数: 0

摘要

Norberto, Matheus S., João Victor G. Torini, Matheus S. Firmino, and Marcelo Papoti.运动中缺氧暴露的空气储存系统验证。00:000-000, 2024.考虑到优化常压缺氧暴露(即更高的输送能力)的重要性,本研究旨在验证缺氧空气储存系统。研究采用交叉、单盲随机设计。空气储存器由一个管道系统组成,该系统将缺氧空气从缺氧发生器导入尼龙袋。16 名男性(年龄,25.4 ± 4.8 岁;身高,174.9 ± 9.4 厘米;体重,77.1 ± 17.2 千克)在不同的日期进行了三次增量跑步机测试,直至力竭。为了进行重复测试,受试者在相似的低氧条件下(H1 和 H2;吸入氧气分数 [FIO2] = ∼ 0.13;可靠性分析)重复了两次测试,并在常氧条件下(FIO2 = ∼ 0.20;条件比较)重复了一次测试。对受试者的表现、血乳酸浓度([La-])、动脉血氧饱和度(SpO2)、耗氧量(VO2)、心率(HR)和几个呼吸衍生变量进行了评估。对休息阶段、中等强度阶段和力竭阶段进行了比较。所有变量的比较均采用弗里德曼检验和 Durbin-Conover post hoc(P < 0.05)。缺氧测试-重复测试显示,所有变量均无统计学差异。时间分析表明,两种情况下的 SpO2、心率和心肺变量表现相似(P < 0.01)。常氧状态下和增量跑步机测试期间的平均 FIO2(20.6 ± 0.2%)高于 H1(13.8 ± 0.8%)和 H2(13.7 ± 0.3%)(P < 0.001)。在中等强度下(正常氧=43.1±8.1;H1=38.7±5.7;H2=35.8±8.8 ml.kg-1.min-1)和力竭阶段(正常氧=52.7±12.5;H1=41.9±8.8;H2=40.5±8.9 ml.kg-1.min-1),正常氧的 VO2 反应高于缺氧时的 VO2 反应(p < 0.01)。在所有时刻,SpO2 和 HR 均显示出极好的类内相关系数 (ICC),而 VO2、SpO2、通气量与 CO2 生成量之比 (VE/VCO2)、耗氧量与通气量之比 (VE/VO2) 和 HR 显示出中等或良好的 ICC 和变异系数。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Validation of Air Storage System for Hypoxia Exposure During Exercise.

Norberto, Matheus S., João Victor G. Torini, Matheus S. Firmino, and Marcelo Papoti. Validation of air storage system for hypoxia exposure during exercise. High Alt Med Biol. 00:000-000, 2024.-Considering the importance of optimizing normobaric hypoxia exposure (i.e., higher delivery capacity), the current study aims to validate a hypoxic air storage system. The study has a cross-over, one-blind randomized design. The air storage is composed of a piping system that directs hypoxic air from a hypoxia generator into nylon bags. Sixteen men (age, 25.4 ± 4.8 years; height, 174.9 ± 9.4 cm; weight, 77.1 ± 17.2 kg) performed three incremental treadmill tests until exhaustion on different days. For test-retest, the subjects repeated two tests in similar hypoxia conditions (H1 and H2; fraction of inspired O2 [FIO2] = ∼0.13; reliability analysis), and one time in normoxia (FIO2 = ∼0.20; condition comparison). Subjects' performance, blood lactate concentration ([La-]), arterial oxygen saturation (SpO2), oxygen consumption (VO2), heart rate (HR), and several respiratory-derived variables were evaluated. A comparison was made between the rest, moderate intensity, and exhaustion stages. All variables were compared using the Friedman test with Durbin-Conover post hoc (p < 0.05). The hypoxia test-retest showed no statistical differences for any variable. Time analysis showed similar behavior for SpO2, HR, and cardiorespiratory variables (p < 0.01) for both conditions. The mean FIO2 at rest and during the incremental treadmill test was higher for normoxia (20.6 ± 0.2%) than for H1 (13.8 ± 0.8%) and H2 (13.7 ± 0.3%) (p < 0.001). The VO2 response was higher in normoxia than during hypoxia exposure at moderate intensity (Normoxia = 43.1 ± 8.1; H1 = 38.7 ± 5.7; H2 = 35.8 ± 8.8 ml.kg-1.min-1) and at the exhaustion stage (Normoxia = 52.7 ± 12.5; H1 = 41.9 ± 8.8; H2 = 40.5 ± 8.9 ml.kg-1.min-1) (p < 0.01). SpO2 and HR showed excellent intraclass correlation coefficient (ICC) during all moments, whereas VO2, SpO2, ratio between ventilation and CO2 production (VE/VCO2), ratio between oxygen consumption and ventilation (VE/VO2), and HR showed moderate or good ICC and coefficient of variation <9% during hypoxia test-retest exercises. Thus, the air storage system showed validity for its application and reliability in the measurements associated.

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来源期刊
High altitude medicine & biology
High altitude medicine & biology 医学-公共卫生、环境卫生与职业卫生
CiteScore
3.80
自引率
9.50%
发文量
44
审稿时长
>12 weeks
期刊介绍: High Altitude Medicine & Biology is the only peer-reviewed journal covering the medical and biological issues that impact human life at high altitudes. The Journal delivers critical findings on the impact of high altitude on lung and heart disease, appetite and weight loss, pulmonary and cerebral edema, hypertension, dehydration, infertility, and other diseases. It covers the full spectrum of high altitude life sciences from pathology to human and animal ecology.
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