口咽脊索瘤

Almedina Ramas, Merima Kasumovic, Sabrina Uscupsic, Majda Mujic, Lejla Tokic
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摘要

背景:脊索瘤是一种罕见的恶性肿瘤,主要发生于轴状骨骼,但也可能发生在不寻常的部位。然而,也有罕见病例显示,同一患者同时患有累及口咽的 "NOS "脊索瘤和腮腺上皮-肌上皮癌。根据当代研究,脊索瘤是一种罕见的恶性肿瘤,起源于胚胎时期的脊索残基,通常累及颅骨、骶尾骨或椎骨。研究表明,脊索瘤的发病率估计为每年百万分之一。脊索瘤可发生于任何年龄,但最常被诊断为脊索瘤的年龄为 40-60 岁,男性居多:本文旨在回顾一例 74 岁女性腮腺上皮-肌上皮癌患者和一例累及口咽的 "NOS "脊索瘤病例:采用诊断方法对一名患有两种原发性恶性肿瘤的女性患者进行了检查:病例介绍:由于解剖结构复杂,无法通过经口-经咽入路完全切除肿瘤。术中对肿块的触诊显示,从口咽和下咽处开始的粘膜下病变清晰可见,大小为 20x43x46mm,向上部延伸至鼻咽部,向后部延伸至椎管和椎间孔,导致口咽和下咽近乎完全闭塞。患者还接受了腮腺肿瘤囊外切除术。术后进行了姑息性放疗:手术治疗仍是治疗 EMC 的主要方法,对于拒绝手术的患者以及晚期或无法手术的患者,放射治疗势在必行。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Chordoma of the Oropharynx.

Background: Chordoma is a rare malignant neoplasm that predominantly arises from the axial skeleton, but can also develop in unusual locations. However, there are also rare cases of "NOS" chordoma involving the oropharyx and epithelial-myoepithelial carcinoma of the parotid gland in the same patient. According to contemporary research, chordoma is a rare malignant neoplasm that arises from the embryonic remnants of the notochord. and typically involves the clivus, sacrococcygeal bones or vertebrae. Studies have shown that the incidence of chordoma has been estimated to be one per one million people per year. Chordoma can occur at any age, but most commonly it is diagnosed in the 40-60 year old age group with the male predominance.

Objective: The aim of this article was to review the case of a 74-year-old female patient with epithelial-myoepithelial carcinoma of the parotid gland and a case of "NOS" chordoma involving the oropharyx.

Methods: Diagnostic methods were used to examine a female patient with two primary malignant tumors: CT neck scan, CT of paranasal sinuses, ultrasound examination, scintigraphy and operative finding.

Case presentzation: Due to the anatomy complexity, complete resection of the tumor through a transoral-transpharyngeal approach was not possible. Intraoperative palpation of the mass revealed well defined submucosal lesion 20x43x46mm beginning at the level of the oro- and hypopharynx and extending superiorly to the nasopharynx, and posteriorly into the spinal canal and intervertebral foramen causing near complete occlusion of the oro and hypopharynx. The patient also underwent extracapsular dissection of the parotid tumor. Postoperative palliative radiotherapy was performed.

Conclusion: Surgical treatment remains the mainstay of treatment for EMC and radiation is imperative for patients who refuse surgery and for those with advanced or inoperable diseases.

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