肯尼亚农村地区的痴呆症筛查:痴呆症筛查阳性率及其影响。

IF 3.2 3区 医学 Q2 CLINICAL NEUROLOGY
Neuroepidemiology Pub Date : 2024-01-01 Epub Date: 2024-03-19 DOI:10.1159/000536012
Christine W Musyimi, David M Ndetei, Levi A Muyela, Joe Masila, Nicolas Farina
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引用次数: 0

摘要

导言:肯尼亚缺乏有关痴呆症患者人数的数据。本文旨在估算肯尼亚农村地区居住在社区的老年人(60 岁及以上)中可能患有痴呆症的人数:方法:根据经过培训的 10 名社区保健员(CHWs)所服务的集水区,采用方便的方法招募老年人。使用痴呆症社区简易筛查工具(CSI-D)进行筛查,并报告患病率。通过回归分析了解筛查结果与幸福感、社会隔离和就业状况之间的关系(根据年龄、性别、文化程度、地域和社会地位进行调整):在接受痴呆筛查的 3546 名老年人中,有 652 人筛查结果呈阳性(PR = 0.18,95%CIs 0.17 至 0.20)。根据该工具与金标准(临床诊断)的既定灵敏度和特异性对筛查阳性者进行回溯估计,得出患病率为 9.4%(0.09,95%CIs 0.08 至 0.11)。痴呆症筛查阳性与生活质量较差有关(B =-0.17,p 结论:肯尼亚可能有 258,000 名老年人患有痴呆症,他们的生活质量可能较差。我们需要鼓励及时诊断,并开发出更好的方法为肯尼亚和其他资源有限地区的痴呆症患者提供支持。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Dementia Screening in Rural Kenya: The Prevalence and Impact of Screening Positive for Dementia.

Introduction: In Kenya, there is a lack of data on the number of people with dementia. In this article, we aim to estimate the number of community-dwelling older adults (aged 60 years and above) that are potentially living with dementia in rural Kenya.

Methods: Recruitment of older adults occurred through adopting a convenience approach based on the catchment areas served by ten trained community health workers. Screening was conducted using the Brief Community Screening Instrument for Dementia (CSI-D), in which prevalence ratios were reported. Regression analyses were run to understand the association between screening outcome and wellbeing, social isolation, and employment status (adjusted for age, sex, literacy, geography, and social status).

Results: Of the 3,546 older adults who were screened for dementia, 652 screened positive (PR = 0.18, 95% CIs: 0.17-0.20). Back estimating screen positives based on established sensitivity and specificity of the tool against a gold standard (clinical diagnosis), yielded a prevalence of 9.4% (0.09, 95% CIs: 0.08-0.11). Screening positive for dementia was associated with poorer quality of life (B = -0.17, p < 0.001) and loneliness (B = 0.28, p < 0.001).

Conclusion: There are potentially 258,000 older adults living with dementia in Kenya, who likely have poorer outcomes. We need to encourage a timely diagnosis and develop better ways to support people living with dementia in Kenya and other resource-limited settings.

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来源期刊
Neuroepidemiology
Neuroepidemiology 医学-公共卫生、环境卫生与职业卫生
CiteScore
9.90
自引率
1.80%
发文量
49
审稿时长
6-12 weeks
期刊介绍: ''Neuroepidemiology'' is the only internationally recognised peer-reviewed periodical devoted to descriptive, analytical and experimental studies in the epidemiology of neurologic disease. The scope of the journal expands the boundaries of traditional clinical neurology by providing new insights regarding the etiology, determinants, distribution, management and prevention of diseases of the nervous system.
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