对轻度妊娠糖尿病治疗多中心随机试验的思考。

IF 1.4 4区医学 Q3 OBSTETRICS & GYNECOLOGY

Clinical obstetrics and gynecology Pub Date : 2024-06-01 Epub Date: 2024-03-12 DOI:10.1097/GRF.0000000000000858

Mark B Landon

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引用次数: 0

摘要

2006 年的高血糖和不良妊娠结局研究证实了孕产妇血糖与妊娠结局之间的关系，但关于治疗是否有益于妊娠糖尿病（GDM）的争论依然存在。尽管如此，从业人员仍然普遍筛查并治疗被确认为 GDM 的妇女。为了评估筛查和治疗 GDM 的利弊，美国国家儿童健康与人类发展研究所母胎医学科网络设计并开展了一项精心设计的随机对照试验，对象是患有轻度 GDM 的妇女。该试验证实，治疗 GDM 可显著降低围产期和孕产妇的几种重要结局。

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Reflections on the Multicenter Randomized Trial of Treatment for Mild Gestational Diabetes.

After the 2006 hyperglycemia and adverse pregnancy outcomes study, which confirmed the relationship between maternal glycemia and pregnancy outcomes, the debate remained on whether treatment benefited gestational diabetes mellitus (GDM). Nonetheless, practitioners continued to universally screen for and treat women identified as GDM. To assess the benefits and harms of screening and treatment of GDM, the National Institute of Child Health and Human Development Maternal and Fetal Medicine Unit Network designed and conducted a well-designed randomized controlled trial in women with mild GDM. The trial established that treatment of GDM resulted in a significant reduction in several important perinatal and maternal outcomes.

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来源期刊

Clinical obstetrics and gynecology 医学-妇产科学

CiteScore

2.70

自引率

0.00%

发文量

186

审稿时长

3 months

期刊介绍： Each issue of Clinical Obstetrics and Gynecology is a complete symposium on one or two timely topics of interest in obstetrics and gynecology. For each quarterly issue, two prominent guest editors solicit contributions on key clinical topics of interest to practicing physicians. Procedures, current clinical problems, medical and surgical treatments, and effective diagnostic aids are all carefully reviewed in original articles. The result is an instructive resource that dispenses trustworthy clinical guidance that enhances your understanding of key areas of your practice.