Adiana Mohamed Adib, Nursabrina Najwa Salmin, Noraini Kasim, Sui Kiong Ling, Geoffrey A. Cordell, Nor Hadiani Ismail
{"title":"胡椒的代谢物及其生物特性:最新进展","authors":"Adiana Mohamed Adib, Nursabrina Najwa Salmin, Noraini Kasim, Sui Kiong Ling, Geoffrey A. Cordell, Nor Hadiani Ismail","doi":"10.1007/s11101-024-09930-2","DOIUrl":null,"url":null,"abstract":"<div><p><i>Piper sarmentosum</i> (Piperaceae) is a well-recognized traditional medicinal plant and has attracted considerable attention due to its extensive range of pharmacological properties. This review aims to provide a comprehensive overview of the traditional uses, phytochemical constituents, and biological and pharmacological activities associated with <i>P. sarmentosum</i>, focusing on the scientific literature appearing in the period 2012–2023. Published articles were selected from databases including Science Direct, Google Scholar, and those with a digital object identifier (DOI). The traditional uses of <i>P. sarmentosum</i> encompass a wide spectrum of biological activities, including anticancer, anti-osteoporotic, antibacterial, antioxidant, anti-hypertensive, anti-inflammatory, and anti-diabetic characteristics. The leaf part has been utilized in various forms, including crude extracts or standardized extracts, either alone or in combination with other pharmacological agents, for the treatment of diverse ailments in humans. This review highlights the phytochemical constituents of <i>P. sarmentosum</i> and their contributions to its pharmacological activities. Furthermore, it emphasizes the importance of identifying, determining, and standardizing the active constituents to examine the full biological potential of the plant in a reproducible manner. <i>P. sarmentosum</i> emerges as a rich plant source that holds promise for the development of potential standardized medication candidates. However, further research is needed to assess its safety and therapeutic efficacy beyond the existing data based on a standardized preparation. Preserving this valuable medicinal plant asset is crucial for the health benefits of future generations. This review serves as a comprehensive reference for researchers, medicinal plant practitioners, and healthcare professionals, and encourages further investigation into the multifaceted properties of <i>P. sarmentosum</i> paving the way for its optimal and sustainable utilization in contemporary healthcare.</p></div>","PeriodicalId":733,"journal":{"name":"Phytochemistry Reviews","volume":"23 5","pages":"1443 - 1475"},"PeriodicalIF":7.3000,"publicationDate":"2024-03-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"The metabolites of Piper sarmentosum and their biological properties: a recent update\",\"authors\":\"Adiana Mohamed Adib, Nursabrina Najwa Salmin, Noraini Kasim, Sui Kiong Ling, Geoffrey A. Cordell, Nor Hadiani Ismail\",\"doi\":\"10.1007/s11101-024-09930-2\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<div><p><i>Piper sarmentosum</i> (Piperaceae) is a well-recognized traditional medicinal plant and has attracted considerable attention due to its extensive range of pharmacological properties. This review aims to provide a comprehensive overview of the traditional uses, phytochemical constituents, and biological and pharmacological activities associated with <i>P. sarmentosum</i>, focusing on the scientific literature appearing in the period 2012–2023. Published articles were selected from databases including Science Direct, Google Scholar, and those with a digital object identifier (DOI). The traditional uses of <i>P. sarmentosum</i> encompass a wide spectrum of biological activities, including anticancer, anti-osteoporotic, antibacterial, antioxidant, anti-hypertensive, anti-inflammatory, and anti-diabetic characteristics. The leaf part has been utilized in various forms, including crude extracts or standardized extracts, either alone or in combination with other pharmacological agents, for the treatment of diverse ailments in humans. This review highlights the phytochemical constituents of <i>P. sarmentosum</i> and their contributions to its pharmacological activities. Furthermore, it emphasizes the importance of identifying, determining, and standardizing the active constituents to examine the full biological potential of the plant in a reproducible manner. <i>P. sarmentosum</i> emerges as a rich plant source that holds promise for the development of potential standardized medication candidates. However, further research is needed to assess its safety and therapeutic efficacy beyond the existing data based on a standardized preparation. Preserving this valuable medicinal plant asset is crucial for the health benefits of future generations. This review serves as a comprehensive reference for researchers, medicinal plant practitioners, and healthcare professionals, and encourages further investigation into the multifaceted properties of <i>P. sarmentosum</i> paving the way for its optimal and sustainable utilization in contemporary healthcare.</p></div>\",\"PeriodicalId\":733,\"journal\":{\"name\":\"Phytochemistry Reviews\",\"volume\":\"23 5\",\"pages\":\"1443 - 1475\"},\"PeriodicalIF\":7.3000,\"publicationDate\":\"2024-03-10\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Phytochemistry Reviews\",\"FirstCategoryId\":\"99\",\"ListUrlMain\":\"https://link.springer.com/article/10.1007/s11101-024-09930-2\",\"RegionNum\":2,\"RegionCategory\":\"生物学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q1\",\"JCRName\":\"PLANT SCIENCES\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Phytochemistry Reviews","FirstCategoryId":"99","ListUrlMain":"https://link.springer.com/article/10.1007/s11101-024-09930-2","RegionNum":2,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q1","JCRName":"PLANT SCIENCES","Score":null,"Total":0}
引用次数: 0
摘要
胡椒(胡椒科)是一种公认的传统药用植物,因其广泛的药理特性而备受关注。本综述旨在全面概述与 P. sarmentosum 相关的传统用途、植物化学成分以及生物和药理活性,重点关注 2012-2023 年间出现的科学文献。发表的文章选自科学直达(Science Direct)、谷歌学术(Google Scholar)等数据库以及具有数字对象标识符(DOI)的数据库。刺五加的传统用途涵盖了广泛的生物活性,包括抗癌、抗骨质疏松、抗菌、抗氧化、抗高血压、抗炎和抗糖尿病等特性。叶片部分已被以各种形式(包括粗提取物或标准化提取物)单独或与其他药剂结合使用,用于治疗人类的各种疾病。本综述重点介绍了刺五加的植物化学成分及其对药理活性的贡献。此外,它还强调了鉴定、确定和标准化活性成分的重要性,以便以可重复的方式研究该植物的全部生物潜力。刺五加是一种丰富的植物资源,有望开发出潜在的标准化候选药物。然而,除了基于标准化制剂的现有数据外,还需要进一步的研究来评估其安全性和疗效。为了子孙后代的健康,保护这一宝贵的药用植物资产至关重要。这篇综述为研究人员、药用植物从业人员和医疗保健专业人员提供了全面的参考,并鼓励进一步研究刺五加的多方面特性,为其在当代医疗保健中的优化和可持续利用铺平道路。
The metabolites of Piper sarmentosum and their biological properties: a recent update
Piper sarmentosum (Piperaceae) is a well-recognized traditional medicinal plant and has attracted considerable attention due to its extensive range of pharmacological properties. This review aims to provide a comprehensive overview of the traditional uses, phytochemical constituents, and biological and pharmacological activities associated with P. sarmentosum, focusing on the scientific literature appearing in the period 2012–2023. Published articles were selected from databases including Science Direct, Google Scholar, and those with a digital object identifier (DOI). The traditional uses of P. sarmentosum encompass a wide spectrum of biological activities, including anticancer, anti-osteoporotic, antibacterial, antioxidant, anti-hypertensive, anti-inflammatory, and anti-diabetic characteristics. The leaf part has been utilized in various forms, including crude extracts or standardized extracts, either alone or in combination with other pharmacological agents, for the treatment of diverse ailments in humans. This review highlights the phytochemical constituents of P. sarmentosum and their contributions to its pharmacological activities. Furthermore, it emphasizes the importance of identifying, determining, and standardizing the active constituents to examine the full biological potential of the plant in a reproducible manner. P. sarmentosum emerges as a rich plant source that holds promise for the development of potential standardized medication candidates. However, further research is needed to assess its safety and therapeutic efficacy beyond the existing data based on a standardized preparation. Preserving this valuable medicinal plant asset is crucial for the health benefits of future generations. This review serves as a comprehensive reference for researchers, medicinal plant practitioners, and healthcare professionals, and encourages further investigation into the multifaceted properties of P. sarmentosum paving the way for its optimal and sustainable utilization in contemporary healthcare.
期刊介绍:
Phytochemistry Reviews is the sole review journal encompassing all facets of phytochemistry. It publishes peer-reviewed papers in six issues annually, including topical issues often stemming from meetings organized by the Phytochemical Society of Europe. Additionally, the journal welcomes original review papers that contribute to advancing knowledge in various aspects of plant chemistry, function, biosynthesis, effects on plant and animal physiology, pathology, and their application in agriculture and industry. Invited meeting papers are supplemented with additional review papers, providing a comprehensive overview of the current status across all areas of phytochemistry.