随访轻度 COVID-19 患者的认知障碍和炎症特征

IF 2.9 4区医学 Q3 IMMUNOLOGY

Journal of neuroimmunology Pub Date : 2024-03-05 DOI:10.1016/j.jneuroim.2024.578327

Nathália Gualberto Souza-Silva , Daniela Valadão Rosa , Jonas Jardim de Paula , Roney Santos Coimbra , Débora Marques Miranda , Marco Aurélio Romano-Silva

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引用次数: 0

摘要

轻度 COVID-19 感染者会出现长期的认知症状。值得注意的是，这些人中有 26% 在感染 6 个月后出现视觉空间能力障碍。然而，在最初表现出视觉结构障碍的人中，66%的人随着时间的推移症状有所改善或完全逆转。此外，还观察到细胞因子水平的变化，尤其是 CCL11、HGF 和 CXCL10。这些结果表明，持续的认知问题与促炎细胞因子水平升高之间存在潜在联系，值得进一步研究。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

Follow-up of cognitive impairment and inflammatory profile in individuals with mild COVID-19

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Follow-up of cognitive impairment and inflammatory profile in individuals with mild COVID-19

Individuals who experience mild COVID-19 can suffer from long-lasting cognitive symptoms. Notably, 26% of these individuals experience difficulties with visuospatial abilities six months after infection. However, among those who initially exhibited visuoconstructive impairments, 66% showed improvement or complete reversal over time. Additionally, changes in cytokine levels, particularly CCL11, HGF, and CXCL10, were observed. These results suggest a potential link between ongoing cognitive issues and elevated levels of pro-inflammatory cytokines, which merits further investigation.

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来源期刊

Journal of neuroimmunology 医学-免疫学

CiteScore

6.10

自引率

3.00%

发文量

154

审稿时长

37 days

期刊介绍： The Journal of Neuroimmunology affords a forum for the publication of works applying immunologic methodology to the furtherance of the neurological sciences. Studies on all branches of the neurosciences, particularly fundamental and applied neurobiology, neurology, neuropathology, neurochemistry, neurovirology, neuroendocrinology, neuromuscular research, neuropharmacology and psychology, which involve either immunologic methodology (e.g. immunocytochemistry) or fundamental immunology (e.g. antibody and lymphocyte assays), are considered for publication.