考虑微循环功能的动脉旁路移植血液动力学模型

IF 1 4区医学 Q4 ENGINEERING, BIOMEDICAL

Bio-medical materials and engineering Pub Date : 2024-03-05 DOI:10.3233/bme-230145

Fan He, Minru Li, Lu Hua, Tingting Guo

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引用次数: 0

摘要

背景：动脉狭窄的发病率逐年上升。为了更好地诊断和治疗动脉狭窄，数值模拟技术已成为一种流行的方法。目的：建立一个新模型，研究微循环对动脉旁路移植血液动力学的影响。方法：本文考虑了一个严重狭窄的动脉旁路移植模型。该模型的几何形状包括一个狭窄的动脉管和一个直径相同、缝合角为 45°的旁路移植管。通过有限元数值计算考虑流体与结构相互作用模型，并以微循环为出口边界条件模拟流动。分析了血流速度、压力和壁剪应力的变化。结果：结果表明，血液几乎全部流入移植管，吻合处没有再循环区域。结论：考虑微循环功能的动脉旁路移植模型能更合理地模拟血流的生理特性，有助于临床医生诊断和治疗动脉狭窄。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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A hemodynamic model of artery bypass graft considering microcirculation function

BACKGROUND:The incidence of arterial stenosis is increasing year by year. In order to better diagnose and treat arterial stenosis, numerical simulation technology has become a popular method. OBJECTIVE:A novel model is constructed to investigate the influence of microcirculation on the hemodynamicsof artery bypass graft. METHODS:In this paper, a severely narrow artery bypass graft model is considered. The geometric shape includes a narrow artery tube and a bypass graft of the same diameter with a 45° suture angle. The fluid-structure interaction model is considered by finite element numerical calculation, and the flow is simulated with microcirculation as the outlet boundary condition. The changes of blood flow velocity, pressure and wall shear stress are analyzed. RESULTS:The results show that blood almost entirely flows into the graft tube and there is no recirculation area at the anastomosis. CONCLUSION:The artery bypass graft model considering microcirculation function could simulate the physiological characteristics of blood flow more reasonably, and it provide helps for clinicians to diagnose and treat arterial stenosis.

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来源期刊

Bio-medical materials and engineering 工程技术-材料科学：生物材料

CiteScore

1.80

自引率

0.00%

发文量

审稿时长

6 months

期刊介绍： The aim of Bio-Medical Materials and Engineering is to promote the welfare of humans and to help them keep healthy. This international journal is an interdisciplinary journal that publishes original research papers, review articles and brief notes on materials and engineering for biological and medical systems. Articles in this peer-reviewed journal cover a wide range of topics, including, but not limited to: Engineering as applied to improving diagnosis, therapy, and prevention of disease and injury, and better substitutes for damaged or disabled human organs; Studies of biomaterial interactions with the human body, bio-compatibility, interfacial and interaction problems; Biomechanical behavior under biological and/or medical conditions; Mechanical and biological properties of membrane biomaterials; Cellular and tissue engineering, physiological, biophysical, biochemical bioengineering aspects; Implant failure fields and degradation of implants. Biomimetics engineering and materials including system analysis as supporter for aged people and as rehabilitation; Bioengineering and materials technology as applied to the decontamination against environmental problems; Biosensors, bioreactors, bioprocess instrumentation and control system; Application to food engineering; Standardization problems on biomaterials and related products; Assessment of reliability and safety of biomedical materials and man-machine systems; and Product liability of biomaterials and related products.