Sabit Sarikaya, Ozge Altas, Mustafa Mert Ozgur, Hakan Hancer, Betul Ayca Ozdere, Tanil Ozer, Mehmet Aksut, Murat Bulent Rabus, Kamile Ozeren Topcu, Tolga Bas, Kaan Kirali
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引用次数: 0
摘要
研究目的本研究旨在评估胡桃夹综合征患者的治疗效果，这些患者的症状可以忍受，并且接受了保守治疗，没有进行侵入性干预：这项前瞻性研究包括接受保守治疗的患者。方法：这项前瞻性研究包括接受保守治疗的患者，促进体重增加，研究终点为症状的自发缓解：16名患者（75%为女性，平均年龄（24.4 ± 3.5）岁）接受了保守治疗。在平均 27.3 个月[13-42 个月，四分位数间距 (IQR)]的随访中，直径比（5.5 [5-6.5, IQR] vs 4.3 [4.1-6], p = NS）、峰值速度比（6 [5-7, IQR] vs 4.8 [4.8-5.8]，p = NS）、喙角（27° [24-30, IQR] vs 29° [24-32]；p = NS）和主动脉与肠道夹角（26° [23-29, IQR] vs 28° [24-30]；p = NS）均无统计学意义上的显著变化。症状完全缓解和改善的比例分别为 28.5% 和 31.4%，68.5% 的患者症状保持不变：本研究表明，保守疗法有助于症状轻微的年轻成人患者自发改善或完全缓解症状。
Outcomes of conservative management in patients with nutcracker syndrome.
Objective: This study aims to evaluate outcomes in nutcracker syndrome patients with tolerable symptoms and treated conservatively without invasive interventions.
Methods: This prospective study included patients treated conservatively. Promoting weight gain, the endpoint of the study was spontaneous resolution of symptoms.
Results: Sixteen patients (75% female and mean age 24.4 ± 3.5 years) underwent conservative management. Over a mean follow-up of 27.3 months [13-42, interquartile range (IQR)], the diameter ratio (5.5 [5-6.5, IQR] vs 4.3 [4.1-6], p = NS), the peak velocity ratio (6 [5-7, IQR] vs 4.8 [4.8-5.8], p = NS), beak angle (27° [24-30, IQR] vs 29° [24-32]; p = NS), and aortomesenteric angle (26° [23-29, IQR] vs 28° [24-30]; p = NS) exhibited no statistically significant changes. Complete resolution and improvement of symptoms were 28.5% and 31.4%, respectively, while 68.5% remained unchanged.
Conclusions: This study shows that a conservative approach contributes to the spontaneous improvement or complete resolution in young adult patients with mild symptoms.
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