Uğur Çağlayan , Sedat Gündoğdu , Tiffany M. Ramos , Kristian Syberg
{"title":"静脉注射高渗液体是人类接触微塑料的来源。","authors":"Uğur Çağlayan , Sedat Gündoğdu , Tiffany M. Ramos , Kristian Syberg","doi":"10.1016/j.etap.2024.104411","DOIUrl":null,"url":null,"abstract":"<div><p>This study investigates the presence of microplastics (MPs) in hypertonic fluid solutions, a widely used medical treatment packaged predominantly in plastic. For this purpose, in this study, 13 hypertonic fluid samples from different brands and two different types of packaging (polypropylene and polyvinyl chloride) were analyzed using visual particle counting, µ-Raman microscopy and ATR-FTIR. The results reveal the pervasive presence of MPs in all samples, with an estimated average concentration of 62.82 ± 72.38 MPs/1000 mL. There was no statistically significant difference in MP concentration between PP and PVC packaging. The particles predominantly consisted of fragments (74.1%) and fibers (25.9%), ranging in size from 0.04 to 2.37 mm. µ-Raman analysis identified 12 synthetic polymers as well as cellulose, with polyethylene and cellulose being the most prevalent.</p><p>In conclusion, this study underscores the alarming presence of MPs in hypertonic fluid solutions, raising concerns about potential health risks.</p></div>","PeriodicalId":11775,"journal":{"name":"Environmental toxicology and pharmacology","volume":"107 ","pages":"Article 104411"},"PeriodicalIF":4.2000,"publicationDate":"2024-03-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Intravenous hypertonic fluids as a source of human microplastic exposure\",\"authors\":\"Uğur Çağlayan , Sedat Gündoğdu , Tiffany M. Ramos , Kristian Syberg\",\"doi\":\"10.1016/j.etap.2024.104411\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<div><p>This study investigates the presence of microplastics (MPs) in hypertonic fluid solutions, a widely used medical treatment packaged predominantly in plastic. For this purpose, in this study, 13 hypertonic fluid samples from different brands and two different types of packaging (polypropylene and polyvinyl chloride) were analyzed using visual particle counting, µ-Raman microscopy and ATR-FTIR. The results reveal the pervasive presence of MPs in all samples, with an estimated average concentration of 62.82 ± 72.38 MPs/1000 mL. There was no statistically significant difference in MP concentration between PP and PVC packaging. The particles predominantly consisted of fragments (74.1%) and fibers (25.9%), ranging in size from 0.04 to 2.37 mm. µ-Raman analysis identified 12 synthetic polymers as well as cellulose, with polyethylene and cellulose being the most prevalent.</p><p>In conclusion, this study underscores the alarming presence of MPs in hypertonic fluid solutions, raising concerns about potential health risks.</p></div>\",\"PeriodicalId\":11775,\"journal\":{\"name\":\"Environmental toxicology and pharmacology\",\"volume\":\"107 \",\"pages\":\"Article 104411\"},\"PeriodicalIF\":4.2000,\"publicationDate\":\"2024-03-05\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Environmental toxicology and pharmacology\",\"FirstCategoryId\":\"93\",\"ListUrlMain\":\"https://www.sciencedirect.com/science/article/pii/S1382668924000516\",\"RegionNum\":3,\"RegionCategory\":\"环境科学与生态学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q2\",\"JCRName\":\"ENVIRONMENTAL SCIENCES\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Environmental toxicology and pharmacology","FirstCategoryId":"93","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S1382668924000516","RegionNum":3,"RegionCategory":"环境科学与生态学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q2","JCRName":"ENVIRONMENTAL SCIENCES","Score":null,"Total":0}
Intravenous hypertonic fluids as a source of human microplastic exposure
This study investigates the presence of microplastics (MPs) in hypertonic fluid solutions, a widely used medical treatment packaged predominantly in plastic. For this purpose, in this study, 13 hypertonic fluid samples from different brands and two different types of packaging (polypropylene and polyvinyl chloride) were analyzed using visual particle counting, µ-Raman microscopy and ATR-FTIR. The results reveal the pervasive presence of MPs in all samples, with an estimated average concentration of 62.82 ± 72.38 MPs/1000 mL. There was no statistically significant difference in MP concentration between PP and PVC packaging. The particles predominantly consisted of fragments (74.1%) and fibers (25.9%), ranging in size from 0.04 to 2.37 mm. µ-Raman analysis identified 12 synthetic polymers as well as cellulose, with polyethylene and cellulose being the most prevalent.
In conclusion, this study underscores the alarming presence of MPs in hypertonic fluid solutions, raising concerns about potential health risks.
期刊介绍：
Environmental Toxicology and Pharmacology publishes the results of studies concerning toxic and pharmacological effects of (human and veterinary) drugs and of environmental contaminants in animals and man.
Areas of special interest are: molecular mechanisms of toxicity, biotransformation and toxicokinetics (including toxicokinetic modelling), molecular, biochemical and physiological mechanisms explaining differences in sensitivity between species and individuals, the characterisation of pathophysiological models and mechanisms involved in the development of effects and the identification of biological markers that can be used to study exposure and effects in man and animals.
In addition to full length papers, short communications, full-length reviews and mini-reviews, Environmental Toxicology and Pharmacology will publish in depth assessments of special problem areas. The latter publications may exceed the length of a full length paper three to fourfold. A basic requirement is that the assessments are made under the auspices of international groups of leading experts in the fields concerned. The information examined may either consist of data that were already published, or of new data that were obtained within the framework of collaborative research programmes. Provision is also made for the acceptance of minireviews on (classes of) compounds, toxicities or mechanisms, debating recent advances in rapidly developing fields that fall within the scope of the journal.
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