{"title":"使用体积调制弧疗法进行颅脊柱照射时，基于知识和人工规划的剂量测定与效率比较。","authors":"Wei-Ta Tsai, Hui-Ling Hsieh, Shih-Kai Hung, Chi-Fu Zeng, Ming-Fen Lee, Po-Hao Lin, Chia-Yi Lin, Wei-Chih Li, Wen-Yen Chiou, Tung-Hsin Wu","doi":"10.2478/raon-2024-0018","DOIUrl":null,"url":null,"abstract":"<p><strong>Background: </strong>Craniospinal irradiation (CSI) poses a challenge to treatment planning due to the large target, field junction, and multiple organs at risk (OARs) involved. The aim of this study was to evaluate the performance of knowledge-based planning (KBP) in CSI by comparing original manual plans (MP), KBP RapidPlan initial plans (RP<sub>I</sub>), and KBP RapidPlan final plans (RP<sub>F</sub>), which received further re-optimization to meet the dose constraints.</p><p><strong>Patients and methods: </strong>Dose distributions in the target were evaluated in terms of coverage, mean dose, conformity index (CI), and homogeneity index (HI). The dosimetric results of OARs, planning time, and monitor unit (MU) were evaluated.</p><p><strong>Results: </strong>All MP and RP<sub>F</sub> plans met the plan goals, and 89.36% of RP<sub>I</sub> plans met the plan goals. The Wilcoxon tests showed comparable target coverage, CI, and HI for the MP and RP<sub>F</sub> groups; however, worst plan quality was demonstrated in the RP<sub>I</sub> plans than in MP and RP<sub>F</sub>. For the OARs, RP<sub>F</sub> and RP<sub>I</sub> groups had better dosimetric results than the MP group (<i>P</i> < 0.05 for optic nerves, eyes, parotid glands, and heart). The planning time was significantly reduced by the KBP from an average of 677.80 min in MP to 227.66 min (<i>P</i> < 0.05) and 307.76 min (<i>P</i> < 0.05) in RP<sub>I</sub>, and RP<sub>F</sub>, respectively. MU was not significantly different between these three groups.</p><p><strong>Conclusions: </strong>The KBP can significantly reduce planning time in CSI. Manual re-optimization after the initial KBP is recommended to enhance the plan quality.</p>","PeriodicalId":21034,"journal":{"name":"Radiology and Oncology","volume":" ","pages":"289-299"},"PeriodicalIF":2.1000,"publicationDate":"2024-03-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11165983/pdf/","citationCount":"0","resultStr":"{\"title\":\"Dosimetry and efficiency comparison of knowledge-based and manual planning using volumetric modulated arc therapy for craniospinal irradiation.\",\"authors\":\"Wei-Ta Tsai, Hui-Ling Hsieh, Shih-Kai Hung, Chi-Fu Zeng, Ming-Fen Lee, Po-Hao Lin, Chia-Yi Lin, Wei-Chih Li, Wen-Yen Chiou, Tung-Hsin Wu\",\"doi\":\"10.2478/raon-2024-0018\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><strong>Background: </strong>Craniospinal irradiation (CSI) poses a challenge to treatment planning due to the large target, field junction, and multiple organs at risk (OARs) involved. The aim of this study was to evaluate the performance of knowledge-based planning (KBP) in CSI by comparing original manual plans (MP), KBP RapidPlan initial plans (RP<sub>I</sub>), and KBP RapidPlan final plans (RP<sub>F</sub>), which received further re-optimization to meet the dose constraints.</p><p><strong>Patients and methods: </strong>Dose distributions in the target were evaluated in terms of coverage, mean dose, conformity index (CI), and homogeneity index (HI). The dosimetric results of OARs, planning time, and monitor unit (MU) were evaluated.</p><p><strong>Results: </strong>All MP and RP<sub>F</sub> plans met the plan goals, and 89.36% of RP<sub>I</sub> plans met the plan goals. The Wilcoxon tests showed comparable target coverage, CI, and HI for the MP and RP<sub>F</sub> groups; however, worst plan quality was demonstrated in the RP<sub>I</sub> plans than in MP and RP<sub>F</sub>. For the OARs, RP<sub>F</sub> and RP<sub>I</sub> groups had better dosimetric results than the MP group (<i>P</i> < 0.05 for optic nerves, eyes, parotid glands, and heart). The planning time was significantly reduced by the KBP from an average of 677.80 min in MP to 227.66 min (<i>P</i> < 0.05) and 307.76 min (<i>P</i> < 0.05) in RP<sub>I</sub>, and RP<sub>F</sub>, respectively. MU was not significantly different between these three groups.</p><p><strong>Conclusions: </strong>The KBP can significantly reduce planning time in CSI. Manual re-optimization after the initial KBP is recommended to enhance the plan quality.</p>\",\"PeriodicalId\":21034,\"journal\":{\"name\":\"Radiology and Oncology\",\"volume\":\" \",\"pages\":\"289-299\"},\"PeriodicalIF\":2.1000,\"publicationDate\":\"2024-03-07\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11165983/pdf/\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Radiology and Oncology\",\"FirstCategoryId\":\"3\",\"ListUrlMain\":\"https://doi.org/10.2478/raon-2024-0018\",\"RegionNum\":4,\"RegionCategory\":\"医学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"2024/6/1 0:00:00\",\"PubModel\":\"eCollection\",\"JCR\":\"Q3\",\"JCRName\":\"ONCOLOGY\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Radiology and Oncology","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.2478/raon-2024-0018","RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"2024/6/1 0:00:00","PubModel":"eCollection","JCR":"Q3","JCRName":"ONCOLOGY","Score":null,"Total":0}
Dosimetry and efficiency comparison of knowledge-based and manual planning using volumetric modulated arc therapy for craniospinal irradiation.
Background: Craniospinal irradiation (CSI) poses a challenge to treatment planning due to the large target, field junction, and multiple organs at risk (OARs) involved. The aim of this study was to evaluate the performance of knowledge-based planning (KBP) in CSI by comparing original manual plans (MP), KBP RapidPlan initial plans (RPI), and KBP RapidPlan final plans (RPF), which received further re-optimization to meet the dose constraints.
Patients and methods: Dose distributions in the target were evaluated in terms of coverage, mean dose, conformity index (CI), and homogeneity index (HI). The dosimetric results of OARs, planning time, and monitor unit (MU) were evaluated.
Results: All MP and RPF plans met the plan goals, and 89.36% of RPI plans met the plan goals. The Wilcoxon tests showed comparable target coverage, CI, and HI for the MP and RPF groups; however, worst plan quality was demonstrated in the RPI plans than in MP and RPF. For the OARs, RPF and RPI groups had better dosimetric results than the MP group (P < 0.05 for optic nerves, eyes, parotid glands, and heart). The planning time was significantly reduced by the KBP from an average of 677.80 min in MP to 227.66 min (P < 0.05) and 307.76 min (P < 0.05) in RPI, and RPF, respectively. MU was not significantly different between these three groups.
Conclusions: The KBP can significantly reduce planning time in CSI. Manual re-optimization after the initial KBP is recommended to enhance the plan quality.
期刊介绍：
Radiology and Oncology is a multidisciplinary journal devoted to the publishing original and high quality scientific papers and review articles, pertinent to diagnostic and interventional radiology, computerized tomography, magnetic resonance, ultrasound, nuclear medicine, radiotherapy, clinical and experimental oncology, radiobiology, medical physics and radiation protection. Therefore, the scope of the journal is to cover beside radiology the diagnostic and therapeutic aspects in oncology, which distinguishes it from other journals in the field.
求助内容：
应助结果提醒方式：
京公网安备 11010802042870号
